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Postinjury Multiple Organ Failure The Population at Risk Predictors of MOF

Postinjury Multiple Organ Failure : The Population at Risk Predictors of MOF [The severely injured trauma patient, defined as an Injury Severity Score (ISS) > 15, requiring resuscitation and admission to the Intensive Care Unit (ICU) is the population at risk for developing post-injury multiple organ failure (MOF). There have been several predictors for the development of MOF described over the last four decades; these include age, severity of injury, resuscitation and blood transfusion to name a few. Some MOF risk factors have changed over time due to demographic changes and with refinement of shock management and improved critical care management. Identifying the modifiable versus non-modifiable risk factors is the key factor to guiding research and therapeutic strategies to reduce the incidence and impact of post-injury MOF. This chapter will review the statistically proven clinical independent predictors including patient factors, injury factors and treatment factors affecting the population at risk and the predictors for developing MOF.] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png

Postinjury Multiple Organ Failure The Population at Risk Predictors of MOF

Part of the Hot Topics in Acute Care Surgery and Trauma Book Series
Editors: Balogh, Zsolt J.; Coimbra, Raul; Di Saverio, Salomone; Kirkpatrick, Andrew W.; Coccolini, Federico
King, Kate L.; Balogh, Zsolt J.
Postinjury Multiple Organ Failure — Mar 17, 2022
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Publisher
Springer International Publishing
Copyright
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022
ISBN
978-3-030-92240-5
Pages
39 –49
DOI
10.1007/978-3-030-92241-2_4
Publisher site
See Chapter on Publisher Site

Abstract

[The severely injured trauma patient, defined as an Injury Severity Score (ISS) > 15, requiring resuscitation and admission to the Intensive Care Unit (ICU) is the population at risk for developing post-injury multiple organ failure (MOF). There have been several predictors for the development of MOF described over the last four decades; these include age, severity of injury, resuscitation and blood transfusion to name a few. Some MOF risk factors have changed over time due to demographic changes and with refinement of shock management and improved critical care management. Identifying the modifiable versus non-modifiable risk factors is the key factor to guiding research and therapeutic strategies to reduce the incidence and impact of post-injury MOF. This chapter will review the statistically proven clinical independent predictors including patient factors, injury factors and treatment factors affecting the population at risk and the predictors for developing MOF.]

Published: Mar 17, 2022

Keywords: Post-injury multiple organ failure; MOF; Risk factors; Predictors; Trauma; Patient factors; Injury factors; Treatment factors

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