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Prostate-specific antigen, prostate volume and transition zone volume in Japanese patients with histologically proven benign prostatic hyperplasia

Prostate-specific antigen, prostate volume and transition zone volume in Japanese patients with... The relationship among age, prostate-specific antigen (PSA) level andprostate volume in Japanese patients with lower urinary tract symptoms(LUTS) and histologically proven benign prostatic hyperplasia (BPH) wasexamined in order to assess the utility of PSA as a predictor of prostatevolume. Two hundred eighteen patients with LUTS were confirmed to haveBPH by histological examination for the reason of elevated PSA and/orabnormal digital rectal examination finding. Correlation among PSA,prostate volume and transition zone volume were analyzed in patientsclassified into age-stratified groups. Prostate volume increased with age.Mean serum PSA increased with age, and the correlation of PSA and prostatevolume was determined to be statistically significant in each cohort of age.A correlation coefficient ranged from 0.315 to 0.439. In patients with LUTSand clinical BPH, serum PSA increased with age and was related to prostatevolume. PSA might be useful for therapeutic decision making for patientswith symptomatic BPH. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Urology and Nephrology Springer Journals

Prostate-specific antigen, prostate volume and transition zone volume in Japanese patients with histologically proven benign prostatic hyperplasia

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References (19)

Publisher
Springer Journals
Copyright
Copyright © 2001 by Kluwer Academic Publishers
Subject
Medicine & Public Health; Nephrology; Urology
ISSN
0301-1623
eISSN
1573-2584
DOI
10.1023/A:1020539404686
Publisher site
See Article on Publisher Site

Abstract

The relationship among age, prostate-specific antigen (PSA) level andprostate volume in Japanese patients with lower urinary tract symptoms(LUTS) and histologically proven benign prostatic hyperplasia (BPH) wasexamined in order to assess the utility of PSA as a predictor of prostatevolume. Two hundred eighteen patients with LUTS were confirmed to haveBPH by histological examination for the reason of elevated PSA and/orabnormal digital rectal examination finding. Correlation among PSA,prostate volume and transition zone volume were analyzed in patientsclassified into age-stratified groups. Prostate volume increased with age.Mean serum PSA increased with age, and the correlation of PSA and prostatevolume was determined to be statistically significant in each cohort of age.A correlation coefficient ranged from 0.315 to 0.439. In patients with LUTSand clinical BPH, serum PSA increased with age and was related to prostatevolume. PSA might be useful for therapeutic decision making for patientswith symptomatic BPH.

Journal

International Urology and NephrologySpringer Journals

Published: Oct 9, 2004

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