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RNA-Seq: a revolutionary tool for transcriptomics

RNA-Seq: a revolutionary tool for transcriptomics The development of high-throughput DNA sequencing methods provides a new method for mapping and quantifying transcriptomes — RNA sequencing (RNA-Seq). This article explains how RNA-Seq works, the challenges it faces and how it is changing our view of eukaryotic transcriptomes. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nature Reviews Genetics Springer Journals

RNA-Seq: a revolutionary tool for transcriptomics

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References (44)

Publisher
Springer Journals
Copyright
Copyright © 2008 by Nature Publishing Group
Subject
Biomedicine; Biomedicine, general; Human Genetics; Cancer Research; Agriculture; Gene Function; Animal Genetics and Genomics
ISSN
1471-0056
eISSN
1471-0064
DOI
10.1038/nrg2484
Publisher site
See Article on Publisher Site

Abstract

The development of high-throughput DNA sequencing methods provides a new method for mapping and quantifying transcriptomes — RNA sequencing (RNA-Seq). This article explains how RNA-Seq works, the challenges it faces and how it is changing our view of eukaryotic transcriptomes.

Journal

Nature Reviews GeneticsSpringer Journals

Published: Jan 1, 2009

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