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SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci

SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype... ABSTRACTIn multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses of linkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values with a large number of samples has been sought for long. In order to achieve the goal of obtaining meaningful results directly from raw data, we developed a robust and user-friendly software platform with a series of tools for analysis in association study with high efficiency. The platform has been well evaluated by several sets of real data. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Cell Research Springer Journals

SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci

Cell Research , Volume 15 (2) – Feb 1, 2005

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References (7)

Publisher
Springer Journals
Copyright
Copyright © Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2005
Subject
Life Sciences; Life Sciences, general; Cell Biology
ISSN
1001-0602
eISSN
1748-7838
DOI
10.1038/sj.cr.7290272
Publisher site
See Article on Publisher Site

Abstract

ABSTRACTIn multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses of linkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values with a large number of samples has been sought for long. In order to achieve the goal of obtaining meaningful results directly from raw data, we developed a robust and user-friendly software platform with a series of tools for analysis in association study with high efficiency. The platform has been well evaluated by several sets of real data.

Journal

Cell ResearchSpringer Journals

Published: Feb 1, 2005

Keywords: software; linkage disequilibrium; haplotype analysis; genetic association study

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