Access the full text.
Sign up today, get DeepDyve free for 14 days.
S. Chinwong, D. Chinwong, A. Mangklabruks (2017)Daily Consumption of Virgin Coconut Oil Increases High-Density Lipoprotein Cholesterol Levels in Healthy Volunteers: A Randomized Crossover Trial
Evidence-based Complementary and Alternative Medicine : eCAM, 2017
A. Pirillo, A. Catapano (2018)Proprotein Convertase Subtilisin Kexin 9 Inhibitors.
Cardiology clinics, 36 2
Y. Kamisah, Vengadesh Periyah, Kee Lee, Norrashid Noor-Izwan, Amran Nurul-Hamizah, Badlishah Nurul-Iman, Kogilavani Subermaniam, K. Jaarin, A. Azman, O. Faizah, H. Qodriyah (2015)Cardioprotective effect of virgin coconut oil in heated palm oil diet-induced hypertensive rats
Pharmaceutical Biology, 53
(2005)In vivo oral toxicological studies of Nufera virgin coconut oil
T. Burgert, Sara Taksali, J. Dziura, T. Goodman, C. Yeckel, X. Papademetris, R. Constable, R. Weiss, W. Tamborlane, M. Savoye, Aisha Seyal, S. Caprio (2006)Alanine aminotransferase levels and fatty liver in childhood obesity: associations with insulin resistance, adiponectin, and visceral fat.
The Journal of clinical endocrinology and metabolism, 91 11
A. Famurewa, F. Ejezie (2017)Polyphenols isolated from virgin coconut oil attenuate cadmium-induced dyslipidemia and oxidative stress due to their antioxidant properties and potential benefits on cardiovascular risk ratios in rats
Avicenna Journal of Phytomedicine, 8
S. Illam, A. Narayanankutty, A. Raghavamenon (2017)Polyphenols of virgin coconut oil prevent pro-oxidant mediated cell death
Toxicology Mechanisms and Methods, 27
J. Brunzell, M. Davidson, C. Furberg, R. Goldberg, B. Howard, J. Stein, J. Witztum (2008)Lipoprotein management in patients with cardiometabolic risk: consensus conference report from the American Diabetes Association and the American College of Cardiology Foundation.
Journal of the American College of Cardiology, 51 15
A. Famurewa, Chima Ekeleme-Egedigwe, Sophia Nwali, Ngozi Agbo, J. Obi, G. Ezechukwu (2018)Dietary Supplementation with Virgin Coconut Oil Improves Lipid Profile and Hepatic Antioxidant Status and Has Potential Benefits on Cardiovascular Risk Indices in Normal Rats
Journal of Dietary Supplements, 15
M. St-Onge, P. Jones (2003)Greater rise in fat oxidation with medium-chain triglyceride consumption relative to long-chain triglyceride is associated with lower initial body weight and greater loss of subcutaneous adipose tissue
International Journal of Obesity, 27
Souravh Bais, Gurudarshan Singh, Ramica Sharma (2014)Antiobesity and Hypolipidemic Activity of Moringa oleifera Leaves against High Fat Diet-Induced Obesity in Rats
(2019)Coconut oil–scientific facts
A. Cicero, M. Bove, C. Borghi (2018)Pharmacokinetics, pharmacodynamics and clinical efficacy of non-statin treatments for hypercholesterolemia
Expert Opinion on Drug Metabolism & Toxicology, 14
C. Ikewuchi, Chidinma Ikewuchi (2010)Alteration of Plasma Lipid Profile and Atherogenic Indices of Cholesterol Loaded Rats by Tridax Procumbens Linn: Implications for the Management of Obesity and Cardiovascular Diseases
K. Nevin, T. Rajamohan (2008)Influence of virgin coconut oil on blood coagulation factors, lipid levels and LDL oxidation in cholesterol fed Sprague–Dawley rats
E-spen, The European E-journal of Clinical Nutrition and Metabolism, 3
A. Babu, S. Veluswamy, R. Arena, M. Guazzi, C. Lavie (2014)Virgin Coconut Oil and Its Potential Cardioprotective Effects
Postgraduate Medicine, 126
Yung-Hsuan Shen, Wei-Shiung Yang, Tzong-His Lee, Long‐Teng Lee, Ching-Yu Chen, Kuo-Chin Huang (2005)Bright liver and alanine aminotransferase are associated with metabolic syndrome in adults.
Obesity research, 13 7
S. Arunima, T. Rajamohan (2014)Influence of virgin coconut oil-enriched diet on the transcriptional regulation of fatty acid synthesis and oxidation in rats - a comparative study.
The British journal of nutrition, 111 10
(2016)Virgin coconut oil-hot and fermentation process
(2016)2016) Virgin coconut oil–hot and fermentation process. Technical bulletin No.108, centenary publication–43
M. Teng, Y. Zhao, A. Khoo, T. Yeo, Q. Yong, B. Lim (2019)Impact of coconut oil consumption on cardiovascular health: a systematic review and meta-analysis.
H. Takeuchi, S. Sekine, K. Kojima, T. Aoyama (2008)The application of medium-chain fatty acids: edible oil with a suppressing effect on body fat accumulation.
Asia Pacific journal of clinical nutrition, 17 Suppl 1
K. Srinivasan, B. Viswanad, Lydia Asrat, C. Kaul, P. Ramarao (2005)Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening.
Pharmacological research, 52 4
S. Ramesh, R. Pandiselvam, R. Thushara, M. Manikantan, K. Hebbar, S. Beegum, A. Mathew, S. Neenu, S. Shil (2020)Engineering intervention for production of virgin coconut oil by hot process and multivariate analysis of quality attributes of virgin coconut oil extracted by various methods
Journal of Food Process Engineering, 43
Karen Mumme, W. Stonehouse (2015)Effects of medium-chain triglycerides on weight loss and body composition: a meta-analysis of randomized controlled trials.
Journal of the Academy of Nutrition and Dietetics, 115 2
K. Nevin, T. Rajamohan (2004)Beneficial effects of virgin coconut oil on lipid parameters and in vitro LDL oxidation.
Clinical biochemistry, 37 9
W. Friedewald, R. Levy, D. Fredrickson (1972)Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.
Clinical chemistry, 18 6
A. Narayanankutty, Devika Palliyil, K. Kuruvilla, A. Raghavamenon (2018)Virgin coconut oil reverses hepatic steatosis by restoring redox homeostasis and lipid metabolism in male Wistar rats.
Journal of the science of food and agriculture, 98 5
R. Buettner, J. Schölmerich, L. Bollheimer (2007)High‐fat Diets: Modeling the Metabolic Disorders of Human Obesity in Rodents
A. Narayanankutty, R. Mukesh, Shabna Ayoob, S. Ramavarma, I. Suseela, J. Manalil, B. Kuzhivelil, A. Raghavamenon (2015)Virgin coconut oil maintains redox status and improves glycemic conditions in high fructose fed rats
Journal of Food Science and Technology, 53
(2007)Hypolipidimic activity of Eclipta prostrate (L.) leaf extract in atherogenic diet induced hyperlipidemic rats
Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
Effects of hot process-derived virgin coconut oil (VCO) on antiobesity, lipid-lowering and cardio-protection in male Wistar rat models fed with high-fat diet (HFD) were investigated for 7 weeks. The marked increase in body weight, liver weight, epididymal fat weight, and specific growth rate of HFD-fed rats were significantly attenuated when the HFD was supplemented with VCO. Serum lipid profile of VCO-fed rats showed significantly reduced levels of triglycerides, total cholesterol, low and very low-density lipoprotein cholesterol, and non-high-density lipoprotein cholesterol (non-HDL-C), and increment in high-density lipoprotein cholesterol (HDL-C) level. Significant decrease in cardiac risk indices and CHOLINDEX in all the VCO-treated animal groups were observed. Hepatic enzymatic biomarkers associated with HFD-induced liver damage were reversed with the VCO supplementation. Thus, dose-dependent VCO supplementation can be considered as an effective dietary approach to attenuate obesity and to alleviate the risks of cardiovascular diseases.
"Proceedings of the National Academy of Sciences, India Section B:Biological Sciences" – Springer Journals
Published: Jun 1, 2022
Keywords: Virgin coconut oil; Anti-obesity; Cardio-protectant effect; High-fat diet; Hypolipidemia; Hepatosteatosis
Access the full text.
Sign up today, get DeepDyve free for 14 days.