Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Visual Detection of COVID-19 from Materials Aspect

Visual Detection of COVID-19 from Materials Aspect In the recent COVID-19 pandemic, World Health Organization emphasized that early detection is an effective strategy to reduce the spread of SARS-CoV-2 viruses. Several diagnostic methods, such as reverse transcription-polymerase chain reaction (RT-PCR) and lateral flow immunoassay (LFIA), have been applied based on the mechanism of specific recognition and binding of the probes to viruses or viral antigens. Although the remarkable progress, these methods still suffer from inadequate cellular materials or errors in the detection and sampling procedure of nasopharyngeal/oropharyngeal swab collection. Therefore, developing accurate, ultrafast, and visualized detection calls for more advanced materials and technology urgently to fight against the epidemic. In this review, we first summarize the current methodologies for SARS-CoV-2 diagnosis. Then, recent representative examples are introduced based on various output signals (e.g., colorimetric, fluorometric, electronic, acoustic). Finally, we discuss the limitations of the methods and provide our perspectives on priorities for future test development.Graphical Abstract[graphic not available: see fulltext] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Advanced Fiber Materials Springer Journals

Visual Detection of COVID-19 from Materials Aspect

Download PDF
30 pages

Loading next page...
 
/lp/springer-journals/visual-detection-of-covid-19-from-materials-aspect-pGgn6mCiCE
Publisher
Springer Journals
Copyright
Copyright © Donghua University, Shanghai, China 2022
ISSN
2524-7921
eISSN
2524-793X
DOI
10.1007/s42765-022-00179-y
Publisher site
See Article on Publisher Site

Abstract

In the recent COVID-19 pandemic, World Health Organization emphasized that early detection is an effective strategy to reduce the spread of SARS-CoV-2 viruses. Several diagnostic methods, such as reverse transcription-polymerase chain reaction (RT-PCR) and lateral flow immunoassay (LFIA), have been applied based on the mechanism of specific recognition and binding of the probes to viruses or viral antigens. Although the remarkable progress, these methods still suffer from inadequate cellular materials or errors in the detection and sampling procedure of nasopharyngeal/oropharyngeal swab collection. Therefore, developing accurate, ultrafast, and visualized detection calls for more advanced materials and technology urgently to fight against the epidemic. In this review, we first summarize the current methodologies for SARS-CoV-2 diagnosis. Then, recent representative examples are introduced based on various output signals (e.g., colorimetric, fluorometric, electronic, acoustic). Finally, we discuss the limitations of the methods and provide our perspectives on priorities for future test development.Graphical Abstract[graphic not available: see fulltext]

Journal

Advanced Fiber Materials – Springer Journals

Published: Dec 1, 2022

Keywords: COVID-19; Virus diagnosis; Rapid and high-throughput detection; Visual detection; Materials aspects

References

  • COVID-19—navigating the uncharted
    Fauci, AS; Lane, HC; Redfield, RR
  • Characteristics of SARS-CoV-2 and COVID-19
    Hu, B; Guo, H; Zhou, P; Shi, Z-L
  • Systematic literature review on novel corona virus SARS-CoV-2: a threat to human era
    Rajendran, DK; Rajagopal, V; Alagumanian, S; Santhosh Kumar, T; Sathiya Prabhakaran, SP; Kasilingam, D
  • The architecture of SARS-CoV-2 transcriptome
    Kim, D; Lee, J-Y; Yang, J-S; Kim, JW; Kim, VN; Chang, H
  • The impact of the hypoxia-VEGF-vascular permeability on COVID-19-infected patients
    Cao, Y
  • SARS-CoV-2 vaccines
    Creech, CB; Walker, SC; Samuels, RJ
  • SARS-CoV-2 vaccines: status report
    Amanat, F; Krammer, F
  • Maintaining safety with SARS-CoV-2 vaccines
    Castells, MC; Phillips, EJ
  • SARS-CoV-2 vaccines in development
    Krammer, F
  • Pitfalls in SARS-CoV-2 PCR diagnostics
    Wernike, K; Keller, M; Conraths, FJ; Mettenleiter, TC; Groschup, MH; Beer, M
  • Genetic diversity and evolution of SARS-CoV-2
    Phan, T
  • A contemporary review on pathogenesis and immunity of COVID-19 infection
    Mirzaei, R; Karampoor, S; Sholeh, M; Moradi, P; Ranjbar, R; Ghasemi, F
  • COVID-19 pandemic: mechanism, diagnosis, and treatment
    Kumar, V; Doshi, KU; Khan, WH; Rathore, AS
  • Structural and molecular perspectives of SARS-CoV-2
    Kumar, S; Saxena, SK
  • Structure of the RNA-dependent RNA polymerasefrom COVID-19 virus
    Gao, Y; Yan, L; Huang, Y; Liu, F; Zhao, Y; Cao, L; Wang, T; Sun, Q; Ming, Z; Zhang, L; Ge, J; Zheng, L; Zhang, Y; Wang, H; Zhu, Y; Zhu, C; Hu, T; Hua, T; Zhang, B; Yang, X; Li, J; Yang, H; Liu, Z; Xu, W; Guddat, LW; Wang, Q; Lou, Z; Rao, Z
  • Structural characterization of beta-propiolactone inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) particles
    Bagrov, DV; Glukhov, GS; Moiseenko, AV; Karlova, MG; Litvinov, DS; Zaitsev Pcapital, AC; Kozlovskaya, LI; Shishova, AA; Kovpak, AA; Ivin, YY; Piniaeva, AN; Oksanich, AS; Volok, VP; Osolodkin, DI; Ishmukhametov, AA; Egorov, AM; Shaitan, KV; Kirpichnikov, MP; Sokolova, OS
  • Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress
    Mendonca, L; Howe, A; Gilchrist, JB; Sheng, Y; Sun, D; Knight, ML; Zanetti-Domingues, LC; Bateman, B; Krebs, AS; Chen, L; Radecke, J; Li, VD; Ni, T; Kounatidis, I; Koronfel, MA; Szynkiewicz, M; Harkiolaki, M; Martin-Fernandez, ML; James, W; Zhang, P
  • Structural biology of SARS-CoV-2 and implications for therapeutic development
    Yang, H; Rao, Z
  • Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines
    Fernandes, Q; Inchakalody, VP; Merhi, M; Mestiri, S; Taib, N; El-Ella, DMA; Bedhiafi, T; Raza, A; Al-Zaidan, L; Mohsen, MO; Al-Nesf, MAY; Hssain, AA; Yassine, HM; Bachmann, MF; Uddin, S; Dermime, S
  • Recent progress on the diagnosis of 2019 novel coronavirus
    Ren, L; Li, C
  • A new coronavirus associated with human respiratory disease in China
    Wu, F; Zhao, S; Yu, B; Chen, YM; Wang, W; Song, ZG; Hu, Y; Tao, ZW; Tian, JH; Pei, YY; Yuan, ML; Zhang, YL; Dai, FH; Liu, Y; Wang, QM; Zheng, JJ; Xu, L; Holmes, EC; Zhang, YZ
  • Advances in nucleic acid amplification techniques (NAATs): COVID-19 point-of-care diagnostics as an example
    Kang, T; Lu, J; Yu, T; Long, Y; Liu, G
  • Primer design for quantitative real-time PCR for the emerging coronavirus SARS-CoV-2
    Li, D; Zhang, J; Li, J
  • RT-LAMP for rapid diagnosis of coronavirus SARS-CoV-2
    Huang, WE; Lim, B; Hsu, C-C; Xiong, D; Wu, W; Yu, Y; Jia, H; Wang, Y; Zeng, Y; Ji, M; Chang, H; Zhang, X; Wang, H; Cui, Z
  • Loop-Mediated isothermal amplification (LAMP): a rapid, sensitive, specific, and cost-effective point-of-care test for coronaviruses in the context of COVID-19 pandemic
    Augustine, R; Hasan, A; Das, S; Ahmed, R; Mori, Y; Notomi, T; Kevadiya, BD; Thakor, AS
  • A one-step, one-pot CRISPR nucleic acid detection platform (CRISPR-top): application for the diagnosis of COVID-19
    Li, S; Huang, J; Ren, L; Jiang, W; Wang, M; Zhuang, L; Zheng, Q; Yang, R; Zeng, Y; Luu, LDW; Wang, Y; Tai, J
  • Quantitative real-time PCR approaches for microbial community studies in wastewater treatment systems: applications and considerations
    Kim, J; Lim, J; Lee, C
  • Recent advances in methods for the diagnosis of corona virus disease 2019
    Guo, J; Ge, J; Guo, Y
  • Different respiratory samples for COVID-19 detection by standard and direct quantitative RT-PCR: a literature review
    Ahmadzadeh, M; Vahidi, H; Mahboubi, A; Hajifathaliha, F; Nematollahi, L; Mohit, E
  • Loop-mediated isothermal amplification of DNA
    Notomi, T; Okayama, H; Masubuchi, H; Yonekawa, T; Watanabe, K; Amino, N; Hase, T
  • Clinical validation of optimised RT-LAMP for the diagnosis of SARS-CoV-2 infection
    Lim, B; Ratcliff, J; Nawrot, DA; Yu, Y; Sanghani, HR; Hsu, C-C; Peto, L; Evans, S; Hodgson, SH; Skeva, A; Adam, M; Panopoulou, M; Zois, CE; Poncin, K; Vasudevan, SR; Dai, S; Ren, S; Chang, H; Cui, Z; Simmonds, P; Huang, WE; Andersson, MI
  • Colorimetric reverse transcription loop-mediated isothermal amplification (RT-LAMP) as a visual diagnostic platform for the detection of the emerging coronavirus SARS-CoV-2
    Nawattanapaiboon, K; Pasomsub, E; Prombun, P; Wongbunmak, A; Jenjitwanich, A; Mahasupachai, P; Vetcho, P; Chayrach, C; Manatjaroenlap, N; Samphaongern, C; Watthanachockchai, T; Leedorkmai, P; Manopwisedjaroen, S; Akkarawongsapat, R; Thitithanyanont, A; Phanchana, M; Panbangred, W; Chauvatcharin, S; Srikhirin, T
  • Rapid visual detection of SARS-CoV-2 by colorimetric loop-mediated isothermal amplification
    Reynes, B; Serra, F; Palou, A
  • Expanding the MDx toolbox for filarial diagnosis and surveillance
    Alhassan, A; Li, Z; Poole, CB; Carlow, CKS
  • Research progress in technologies based on isothermal amplification of nucleic acids for detection of SARS-CoV-2
    Li, B; Zou, B; Ma, X; Wu, H; Zhang, Y; Zhou, G
  • CRISPR-based approaches for efficient and accurate detection of SARS-CoV-2
    Zhang, W; Liu, K; Zhang, P; Cheng, W; Li, L; Zhang, F; Yu, Z; Li, L; Zhang, X
  • Inhaled ACE2-engineered microfluidic microsphere for intratracheal neutralization of COVID-19 and calming of the cytokine storm
    Wang, Z; Xiang, L; Lin, F; Cai, Z; Ruan, H; Wang, J; Liang, J; Wang, F; Lu, M; Cui, W
  • Portable and visual assays for the detection of SARS-CoV‐2
    Zhang, Y; Ding, D
  • Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants
    de Puig, H; Lee, RA; Najjar, D; Tan, X; Soekensen, LR; Angenent-Mari, NM; Donghia, NM; Weckman, NE; Ory, A; Ng, CF; Nguyen, PQ; Mao, AS; Ferrante, TC; Lansberry, G; Sallum, H; Niemi, J; Collins, JJ
  • Cas12c-DETECTOR: a specific and sensitive Cas12c-based DNA detection platform
    Wang, Z; Zhong, C
  • Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA
    Patchsung, M; Jantarug, K; Pattama, A; Aphicho, K; Suraritdechachai, S; Meesawat, P; Sappakhaw, K; Leelahakorn, N; Ruenkam, T; Wongsatit, T; Athipanyasilp, N; Eiamthong, B; Lakkanasirorat, B; Phoodokmai, T; Niljianskul, N; Pakotiprapha, D; Chanarat, S; Homchan, A; Tinikul, R; Kamutira, P; Phiwkaow, K; Soithongcharoen, S; Kantiwiriyawanitch, C; Pongsupasa, V; Trisrivirat, D; Jaroensuk, J; Wongnate, T; Maenpuen, S; Chaiyen, P; Kamnerdnakta, S; Swangsri, J; Chuthapisith, S; Sirivatanauksorn, Y; Chaimayo, C; Sutthent, R; Kantakamalakul, W; Joung, J; Ladha, A; Jin, X; Gootenberg, JS; Abudayyeh, OO; Zhang, F; Horthongkham, N; Uttamapinant, C
  • CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
    Chen, JS; Ma, E; Harrington, LB; Da Costa, M; Tian, X; Palefsky, JM; Doudna, JA
  • CRISPR-Cas12-based detection of SARS-CoV-2
    Broughton, JP; Deng, X; Yu, G; Fasching, CL; Servellita, V; Singh, J; Miao, X; Streithorst, JA; Granados, A; Sotomayor-Gonzalez, A; Zorn, K; Gopez, A; Hsu, E; Gu, W; Miller, S; Pan, CY; Guevara, H; Wadford, DA; Chen, JS; Chiu, CY
  • First CRISPR test for the coronavirus approved in the United States
    Guglielmi, G
  • Performance and application evaluation of SARS-CoV-2 antigen assay
    Ye, Q; Shao, W; Meng, H
  • Rapid antigen tests for the detection of SARS-CoV-2: a narrative review
    Aguilar-Shea, AL; Vera-Garcia, M; Guerri-Fernandez, R
  • Development and efficacy of lateral flow point-of-care testing devices for rapid and mass COVID-19 diagnosis by the detections of SARS-CoV-2 antigen and anti-SARS-CoV-2 antibodies
    Hsieh, W-Y; Lin, C-H; Lin, T-C; Lin, C-H; Chang, H-F; Tsai, C-H; Wu, H-T; Lin, C-S
  • Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis
    Li, Z; Yi, Y; Luo, X; Xiong, N; Liu, Y; Li, S; Sun, R; Wang, Y; Hu, B; Chen, W; Zhang, Y; Wang, J; Huang, B; Lin, Y; Yang, J; Cai, W; Wang, X; Cheng, J; Chen, Z; Sun, K; Pan, W; Zhan, Z; Chen, L; Ye, F
  • Diagnostic techniques for COVID-19: a mini-review of early diagnostic methods
    Dong, G-P; Guo, X-J; Sun, Y-A; Zhang, Z; Du, L-P; Li, M-Y
  • Development of diagnostic tests for detection of SARS-CoV-2
    Nguyen, NNT; McCarthy, C; Lantigua, D; Camci-Unal, G
  • C SA-C-TES. A dual-antigen enzyme-linked immunosorbent assay allows the assessment of severe acute respiratory syndrome coronavirus 2 antibody seroprevalence in a low-transmission setting
    Hicks, SM; Pohl, K; Neeman, T; McNamara, HA; Parsons, KM; He, J-s; Ali, SA; Nazir, S; Rowntree, LC; Nguyen, THO; Kedzierska, K; Doolan, DL; Vinuesa, CG; Cook, MC; Coatsworth, N; Myles, PS; Kurth, F; Sander, LE; Mann, GJ; Gruen, RL; George, AJ; Gardiner, EE; Cockburn, IA
  • Novel approaches for rapid detection of COVID-19 during the pandemic: a review
    Ilkhani, H; Hedayat, N; Farhad, S
  • Imaging manifestations and diagnostic value of chest CT of coronavirus disease 2019 (COVID-19) in the Xiaogan area
    Wang, K; Kang, S; Tian, R; Zhang, X; Wang, Y
  • Chest computed tomography for detection of coronavirus disease 2019 (COVID-19): Don’t rush the science
    Hope, MD; Raptis, CA; Henry, TS
  • Diagnostic techniques for COVID-19: a mini-review
    Wu, X; Chen, Q; Li, J; Liu, Z
  • Development of a SARS-CoV-2-specific biosensor for antigen detection using scFv-Fc fusion proteins
    Kim, HY; Lee, JH; Kim, MJ; Park, SC; Choi, M; Lee, W; Ku, KB; Kim, BT; Changkyun Park, E; Kim, HG; Kim, SI
  • Evaluation of rapid antigen test for detection of SARS-CoV-2 virus
    Mak, GC; Cheng, PK; Lau, SS; Wong, KK; Lau, CS; Lam, ET; Chan, RC; Tsang, DN
  • Low performance of rapid antigen detection test as frontline testing for COVID-19 diagnosis
    Scohy, A; Anantharajah, A; Bodeus, M; Kabamba-Mukadi, B; Verroken, A; Rodriguez-Villalobos, H
  • Emerging diagnostic tools for detection of COVID-19 and perspective
    Verma, N; Patel, D; Pandya, A
  • Comparative evaluation of four rapid SARS-CoV-2 antigen detection tests using universal transport medium
    Weitzel, T; Legarraga, P; Iruretagoyena, M; Pizarro, G; Vollrath, V; Araos, R; Munita, JM; Porte, L
  • Multiplex reverse transcription loop-mediated isothermal amplification combined with nanoparticle-based lateral flow biosensor for the diagnosis of COVID-19
    Zhu, X; Wang, X; Han, L; Chen, T; Wang, L; Li, H; Li, S; He, L; Fu, X; Chen, S; Xing, M; Chen, H; Wang, Y
  • Diagnostic utility of antigen detection rapid diagnostic tests for COVID-19: a systematic review and meta-analysis
    Ghasemi, S; Harmooshi, NN; Rahim, F
  • State of the art on the SARS-CoV-2 toolkit for antigen detection: one year later
    Fabiani, L; Caratelli, V; Fiore, L; Scognamiglio, V; Antonacci, A; Fillo, S; De Santis, R; Monte, A; Bortone, M; Moscone, D; Lista, F; Arduini, F
  • Massively multiplexed nucleic acid detection with Cas13
    Ackerman, CM; Myhrvold, C; Thakku, SG; Freije, CA; Metsky, HC; Yang, DK; Ye, SH; Boehm, CK; Kosoko-Thoroddsen, TF; Kehe, J; Nguyen, TG; Carter, A; Kulesa, A; Barnes, JR; Dugan, VG; Hung, DT; Blainey, PC; Sabeti, PC
  • CRISPR/Cas systems towards next-generation biosensing
    Li, Y; Li, S; Wang, J; Liu, G
  • Wearable materials with embedded synthetic biology sensors for biomolecule detection
    Nguyen, PQ; Soenksen, LR; Donghia, NM; Angenent-Mari, NM; de Puig, H; Huang, A; Lee, R; Slomovic, S; Galbersanini, T; Lansberry, G; Sallum, HM; Zhao, EM; Niemi, JB; Collins, JJ
  • Selective naked-eye detection of SARS-CoV-2 mediated by N gene targeted antisense oligonucleotide capped plasmonic nanoparticles
    Moitra, P; Alafeef, M; Dighe, K; Frieman, MB; Pan, D
  • A rapid, simple, inexpensive, and mobile colorimetric assay COVID-19-LAMP for mass on-site screening of COVID-19
    Chow, FW; Chan, TT; Tam, AR; Zhao, S; Yao, W; Fung, J; Cheng, FK; Lo, GC; Chu, S; Aw-Yong, KL; Tang, JY; Tsang, CC; Luk, HK; Wong, AC; Li, KS; Zhu, L; He, Z; Tam, EWT; Chung, TW; Wong, SCY; Que, TL; Fung, KS; Lung, DC; Wu, AK; Hung, IF; Woo, PC; Lau, SK
  • Label-free immunoassay for sensitive and rapid detection of the SARS-CoV-2 antigen based on functionalized magnetic nanobeads with chemiluminescence and immunoactivity
    Wang, S; Shu, J; Lyu, A; Huang, X; Zeng, W; Jin, T; Cui, H
  • Nanozyme chemiluminescence paper test for rapid and sensitive detection of SARS-CoV-2 antigen
    Liu, D; Ju, C; Han, C; Shi, R; Chen, X; Duan, D; Yan, J; Yan, X
  • Raman spectra of pyridine adsorbed at a silver electrode
    Fleischmann, M; Hendra, PJ; Mcquillan, AJ
  • Single molecule detection using surface-enhanced Raman scattering (SERS)
    Katrin Kneipp, Y; Wang, H; Kneipp, Lev, T; Perelman, I; Itzkan, Ramachandra, R; Dasari, MSF
  • Probing single molecules and single nanoparticles by surface-enhanced Raman scattering
    Shuming Nie, Emory, SR
  • Present and future of surface-enhanced Raman scattering
    Langer, J; Jimenez de Aberasturi, D; Aizpurua, J; Alvarez-Puebla, RA; Auguie, B; Baumberg, JJ; Bazan, GC; Bell, SEJ; Boisen, A; Brolo, AG; Choo, J; Cialla-May, D; Deckert, V; Fabris, L; Faulds, K; Garcia de Abajo, FJ; Goodacre, R; Graham, D; Haes, AJ; Haynes, CL; Huck, C; Itoh, T; Kall, M; Kneipp, J; Kotov, NA; Kuang, H; Le Ru, EC; Lee, HK; Li, JF; Ling, XY; Maier, SA; Mayerhofer, T; Moskovits, M; Murakoshi, K; Nam, JM; Nie, S; Ozaki, Y; Pastoriza-Santos, I; Perez-Juste, J; Popp, J; Pucci, A; Reich, S; Ren, B; Schatz, GC; Shegai, T; Schlucker, S; Tay, LL; Thomas, KG; Tian, ZQ; Van Duyne, RP; Vo-Dinh, T; Wang, Y; Willets, KA; Xu, C; Xu, H; Xu, Y; Yamamoto, YS; Zhao, B; Liz-Marzan, LM
  • Exploring the margins of SERS in practical domain: an emerging diagnostic modality for modern biomedical applications
    Joseph, MM; Narayanan, N; Nair, JB; Karunakaran, V; Ramya, AN; Sujai, PT; Saranya, G; Arya, JS; Vijayan, VM; Maiti, KK
  • SERS based lateral flow immunoassay for point-of-care detection of SARS-CoV-2 in clinical samples
    Yadav, S; Sadique, MA; Ranjan, P; Kumar, N; Singhal, A; Srivastava, AK; Khan, R
  • Rapid and sensitive SERS-based lateral flow test for SARS-CoV2-specific IgM/IgG antibodies
    Srivastav, S; Dankov, A; Adanalic, M; Grzeschik, R; Tran, V; Pagel-Wieder, S; Gessler, F; Spreitzer, I; Scholz, T; Schnierle, B; Anastasiou, OE; Dittmer, U; Schlucker, S
  • Charge-transfer resonance and electromagnetic enhancement synergistically enabling mxenes with excellent SERS sensitivity for SARS-CoV-2 S protein detection
    Peng, Y; Lin, C; Long, L; Masaki, T; Tang, M; Yang, L; Liu, J; Huang, Z; Li, Z; Luo, X; Lombardi, JR; Yang, Y
  • Human ACE2-functionalized gold “virus-trap” nanostructures for accurate capture of SARS-CoV-2 and single-virus SERS detection
    Yang, Y; Peng, Y; Lin, C; Long, L; Hu, J; He, J; Zeng, H; Huang, Z; Li, ZY; Tanemura, M; Shi, J; Lombardi, JR; Luo, X
  • Construction of optimal SERS hotspots based on capturing the spike receptor-binding domain (RBD) of SARS-CoV-2 for highly sensitive and specific detection by a fish model
    Huang, G; Zhao, H; Li, P; Liu, J; Chen, S; Ge, M; Qin, M; Zhou, G; Wang, Y; Li, S; Cheng, Y; Huang, Q; Wang, J; Wang, H; Yang, L
  • Development of a SERS-based lateral flow immunoassay for rapid and ultra-sensitive detection of anti-SARS-CoV-2 IgM/IgG in clinical samples
    Liu, H; Dai, E; Xiao, R; Zhou, Z; Zhang, M; Bai, Z; Shao, Y; Qi, K; Tu, J; Wang, C; Wang, S
  • Noninvasive and point-of-care surface-enhanced raman scattering (SERS)-based breathalyzer for mass screening of coronavirus disease 2019 (COVID-19) under 5 min
    Leong, SX; Leong, YX; Tan, EX; Sim, HYF; Koh, CSL; Lee, YH; Chong, C; Ng, LS; Chen, JRT; Pang, DWC; Nguyen, LBT; Boong, SK; Han, X; Kao, YC; Chua, YH; Phan-Quang, GC; Phang, IY; Lee, HK; Abdad, MY; Tan, NS; Ling, XY
  • Surface-enhanced Raman spectroscopy
    Han, XX; Rodriguez, RS; Haynes, CL; Ozaki, Y; Zhao, B
  • Electrode systems for continuous monitoring in cardiovascular surgery
    Leland, C; Clark, Lyons, C
  • The potential application of electrochemical biosensors in the COVID-19 pandemic: A perspective on the rapid diagnostics of SARS-CoV-2
    Mahshid, SS; Flynn, SE; Mahshid, S
  • Perspectives on electrochemical biosensing of COVID-19
    Luong, AD; Buzid, A; Vashist, SK; Luong, JHT
  • SPEEDS: A portable serological testing platform for rapid electrochemical detection of SARS-CoV-2 antibodies
    Peng, R; Pan, Y; Li, Z; Qin, Z; Rini, JM; Liu, X
  • Electrochemical SARS-CoV-2 sensing at point-of-care and artificial intelligence for intelligent COVID-19 management
    Kaushik, AK; Dhau, JS; Gohel, H; Mishra, YK; Kateb, B; Kim, NY; Goswami, DY
  • An electrochemical dual-aptamer biosensor based on metal-organic frameworks MIL-53 decorated with Au@Pt nanoparticles and enzymes for detection of COVID-19 nucleocapsid protein
    Tian, J; Liang, Z; Hu, O; He, Q; Sun, D; Chen, Z
  • Minute-scale detection of SARS-CoV-2 using a low-cost biosensor composed of pencil graphite electrodes
    de Lima, LF; Ferreira, AL; Torres, MDT; de Araujo, WR; de la Fuente-Nunez, C
  • Development of a low-cost cotton-tipped electrochemical immunosensor for the detection of SARS-CoV-2
    Eissa, S; Zourob, M
  • Rapid, Ultrasensitive, and quantitative detection of SARS-CoV-2 using antisense oligonucleotides directed electrochemical biosensor chip
    Alafeef, M; Dighe, K; Moitra, P; Pan, D
  • Sensing of COVID-19 antibodies in seconds via aerosol jet nanoprinted reduced-graphene-oxide-coated 3D electrodes
    Ali, MA; Hu, C; Jahan, S; Yuan, B; Saleh, MS; Ju, E; Gao, SJ; Panat, R
  • Rapid and ultrasensitive electromechanical detection of ions, biomolecules and SARS-CoV-2 RNA in unamplified samples
    Wang, L; Wang, X; Wu, Y; Guo, M; Gu, C; Dai, C; Kong, D; Wang, Y; Zhang, C; Qu, D; Fan, C; Xie, Y; Zhu, Z; Liu, Y; Wei, D
  • Rapid single-molecule detection of COVID-19 and MERS antigens via nanobody-functionalized organic electrochemical transistors
    Guo, K; Wustoni, S; Koklu, A; Diaz-Galicia, E; Moser, M; Hama, A; Alqahtani, AA; Ahmad, AN; Alhamlan, FS; Shuaib, M; Pain, A; McCulloch, I; Arold, ST; Grunberg, R; Inal, S
  • Mass spectrometry analytical responses to the SARS-CoV2 coronavirus in review
    Griffin, JH; Downard, KM
  • Mass spectrometry applied to diagnosis, prognosis, and therapeutic targets identification for the novel coronavirus SARS-CoV-2: a review
    Lima, NM; Fernandes, BLM; Alves, GF; de Souza, JCQ; Siqueira, MM; do Nascimento, MP; Moreira, OBO; Sussulini, A; de Oliveira, MAL
  • Mass spectrometry techniques in emerging pathogens studies: COVID-19 perspectives
    Mahmud, I; Garrett, TJ
  • A combined approach of MALDI-TOF mass spectrometry and multivariate analysis as a potential tool for the detection of SARS-CoV-2 virus in nasopharyngeal swabs
    Rocca, MF; Zintgraff, JC; Dattero, ME; Santos, LS; Ledesma, M; Vay, C; Prieto, M; Benedetti, E; Avaro, M; Russo, M; Nachtigall, FM; Baumeister, E
  • Detection of SARS-CoV-2 in nasal swabs using MALDI-MS
    Nachtigall, FM; Pereira, A; Trofymchuk, OS; Santos, LS
  • COVID-19 automated diagnosis and risk assessment through metabolomics and machine learning
    Delafiori, J; Navarro, LC; Siciliano, RF; de Melo, GC; Busanello, ENB; Nicolau, JC; Sales, GM; de Oliveira, AN; Val, FFA; de Oliveira, DN; Eguti, A; dos Santos, LA; Dalçóquio, TF; Bertolin, AJ; Abreu-Netto, RL; Salsoso, R; Baía-da-Silva, D; Marcondes-Braga, FG; Sampaio, VS; Judice, CC; Costa, FTM; Durán, N; Perroud, MW; Sabino, EC; Lacerda, MVG; Reis, LO; Fávaro, WJ; Monteiro, WM; Rocha, AR; Catharino, RR
  • Establishing a mass spectrometry-based system for rapid detection of SARS-CoV-2 in large clinical sample cohorts
    Cardozo, KHM; Lebkuchen, A; Okai, GG; Schuch, RA; Viana, LG; Olive, AN; Lazari, CdS; Fraga, AM; Granato, CFH; Pintão, MCT; Carvalho, VM
  • Virus-host interactome and proteomic survey reveal potential virulence factors influencing SARS-CoV-2 pathogenesis
    Li, J; Guo, M; Tian, X; Wang, X; Yang, X; Wu, P; Liu, C; Xiao, Z; Qu, Y; Yin, Y; Wang, C; Zhang, Y; Zhu, Z; Liu, Z; Peng, C; Zhu, T; Liang, Q
  • Targeted proteomics as a tool to detect SARS-CoV-2 proteins in clinical specimens
    Bezstarosti, K; Lamers, MM; Doff, WAS; Wever, PC; Thai, KTD; van Kampen, JJA; Haagmans, BL; Demmers, JAA
  • Virus-receptor interactions of glycosylated SARS-CoV-2 spike and human ACE2 receptor
    Zhao, P; Praissman, JL; Grant, OC; Cai, Y; Xiao, T; Rosenbalm, KE; Aoki, K; Kellman, BP; Bridger, R; Barouch, DH; Brindley, MA; Lewis, NE; Tiemeyer, M; Chen, B; Woods, RJ; Wells, L
  • Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by mass spectrometry
    Wandernoth, P; Kriegsmann, K; Groh-Mohanu, C; Daeumer, M; Gohl, P; Harzer, O; Kriegsmann, M; Kriegsmann, J
  • Viral respiratory tract infections in adult patients attending outpatient and emergency departments, Taiwan, 2012–2013: a PCR/electrospray ionization mass spectrometry study
    Shih, H-I; Wang, H-C; Su, I-J; Hsu, H-C; Wang, J-R; Sun, HFS; Chou, C-H; Ko, W-C; Hsieh, M-I; Wu, C-J
  • Biological nanopore approach for single-molecule protein sequencing
    Hu, ZL; Huo, MZ; Ying, YL; Long, YT
  • Multiple rereads of single proteins at single-amino acid resolution using nanopores
    Brinkerhoff, H; Kang, ASW; Liu, JQ; Aksimentiev, A; Dekker, C
  • Decoding long nanopore sequencing reads of natural DNA
    Laszlo, AH; Derrington, IM; Ross, BC; Brinkerhoff, H; Adey, A; Nova, IC; Craig, JM; Langford, KW; Samson, JM; Daza, R; Doering, K; Shendure, J; Gundlach, JH
  • AI4COVID-19: AI enabled preliminary diagnosis for COVID-19 from cough samples via an app
    Imran, A; Posokhova, I; Qureshi, HN; Masood, U; Riaz, MS; Ali, K; John, CN; Hussain, MI; Nabeel, M
  • Novel coronavirus cough database: NoCoCoDa
    Cohen-McFarlane, M; Goubran, R; Knoefel, F
  • The COUGHVID crowdsourcing dataset, a corpus for the study of large-scale cough analysis algorithms
    Orlandic, L; Teijeiro, T; Atienza, D
  • Global applicability of crowdsourced and clinical datasets for AI detection of COVID-19 from cough
    Chaudhari, G; Jiang, X; Fakhry, A; Han, A; Xiao, J; Shen, S; Khanzada, A; Virufy
  • Machine learning for detecting COVID-19 from cough sounds: an ensemble-based MCDM method
    Chowdhury, NK; Kabir, MA; Rahman, MM; Islam, SMS
  • QUCoughScope: an intelligent application to detect COVID-19 patients using cough and breath sounds
    Rahman, T; Ibtehaz, N; Khandakar, A; Hossain, MSA; Mekki, YMS; Ezeddin, M; Bhuiyan, EH; Ayari, MA; Tahir, A; Qiblawey, Y; Mahmud, S; Zughaier, SM; Abbas, T; Al-Maadeed, S; Chowdhury, MEH
  • COVID-19 cough classification using machine learning and global smartphone recordings
    Pahar, M; Klopper, M; Warren, R; Niesler, T
  • Review on COVID-19 diagnosis models based on machine learning and deep learning approaches
    Alyasseri, ZAA; Al-Betar, MA; Doush, IA; Awadallah, MA; Abasi, AK; Makhadmeh, SN; Alomari, OA; Abdulkareem, KH; Adam, A; Damasevicius, R; Mohammed, MA; Zitar, RA
  • COVID-19 diagnosis from crowdsourced cough sound data
    Son, M-J; Lee, S-P
  • Knowledge graph analysis and visualization of AI technology applied in COVID-19
    Wu, Z; Xue, R; Shao, M
  • Recent advances in novel lateral flow technologies for detection of COVID-19
    Hsiao, WW; Le, TN; Pham, DM; Ko, HH; Chang, HC; Lee, CC; Sharma, N; Lee, CK; Chiang, WH
  • Tetra-primer ARMS-PCR combined with dual-color fluorescent lateral flow assay for the discrimination of SARS-CoV-2 and its mutations with a handheld wireless reader
    Wang, Y; Chen, H; Wei, H; Rong, Z; Wang, S
  • Smartphone-based sensitive detection of SARS-CoV-2 from saline gargle samples via flow profile analysis on a paper microfluidic chip
    Akarapipad, P; Kaarj, K; Breshears, LE; Sosnowski, K; Baker, J; Nguyen, BT; Eades, C; Uhrlaub, JL; Quirk, G; Nikolich-Zugich, J; Worobey, M; Yoon, JY
  • Direct capture and smartphone quantification of airborne SARS-CoV-2 on a paper microfluidic chip
    Kim, S; Akarapipad, P; Nguyen, BT; Breshears, LE; Sosnowski, K; Baker, J; Uhrlaub, JL; Nikolich-Zugich, J; Yoon, JY
  • Emulsion-based isothermal nucleic acid amplification for rapid SARS-CoV-2 detection via angle-dependent light scatter analysis
    Day, AS; Ulep, TH; Safavinia, B; Hertenstein, T; Budiman, E; Dieckhaus, L; Yoon, JY
  • Portable real-time colorimetric LAMP-device for rapid quantitative detection of nucleic acids in crude samples
    Papadakis, G; Pantazis, AK; Fikas, N; Chatziioannidou, S; Tsiakalou, V; Michaelidou, K; Pogka, V; Megariti, M; Vardaki, M; Giarentis, K; Heaney, J; Nastouli, E; Karamitros, T; Mentis, A; Zafiropoulos, A; Sourvinos, G; Agelaki, S; Gizeli, E
  • Portable real-time colorimetric LAMP-device for rapid quantitative detection of nucleic acids in crude samples
    Xiao, M; Tian, F; Liu, X; Zhou, Q; Pan, J; Luo, Z; Yang, M; Yi, C
  • Current progress on COVID-19 related to biosensing technologies: new opportunity for detection and monitoring of viruses
    Laghrib, F; Saqrane, S; El Bouabi, Y; Farahi, A; Bakasse, M; Lahrich, S; El Mhammedi, MA
  • Harmony COVID-19: a ready-to-use kit, low-cost detector, and smartphone app for point-of-care SARS-CoV-2 RNA detection
    Panpradist, N; Kline, EC; Atkinson, RG; Roller, M; Wang, Q; Hull, IT; Kotnik, JH; Oreskovic, AK; Bennett, C; Leon, D; Lyon, V; Gilligan-Steinberg, SD; Han, PD; Drain, PK; Starita, LM; Thompson, MJ; Lutz, BR
  • Open-source, adaptable, all-in-one smartphone-based system for quantitative analysis of point-of-care diagnostics
    Schary, W; Paskali, F; Rentschler, S; Ruppert, C; Wagner, GE; Steinmetz, I; Deigner, HP; Kohl, M
  • Ultrasensitive supersandwich-type electrochemical sensor for SARS-CoV-2 from the infected COVID-19 patients using a smartphone
    Zhao, H; Liu, F; Xie, W; Zhou, TC; OuYang, J; Jin, L; Li, H; Zhao, CY; Zhang, L; Wei, J; Zhang, YP; Li, CP
  • Rapid point-of-care COVID-19 diagnosis with a gold-nanoarchitecture-assisted laser-scribed graphene biosensor
    Beduk, T; Beduk, D; de Oliveira Filho, JI; Zihnioglu, F; Cicek, C; Sertoz, R; Arda, B; Goksel, T; Turhan, K; Salama, KN; Timur, S
  • Sample-to-answer COVID-19 nucleic acid testing using a low-cost centrifugal microfluidic platform with bead-based signal enhancement and smartphone read-out
    Soares, RRG; Akhtar, AS; Pinto, IF; Lapins, N; Barrett, D; Sandh, G; Yin, X; Pelechano, V; Russom, A
  • Paper biosensors for detecting elevated IL-6 levels in blood and respiratory samples from COVID-19 patients
    Adrover-Jaume, C; Alba-Patino, A; Clemente, A; Santopolo, G; Vaquer, A; Russell, SM; Baron, E; Gonzalez Del Campo, MDM; Ferrer, JM; Berman-Riu, M; Garcia-Gasalla, M; Aranda, M; Borges, M; de la Rica, R
  • On-board smartphone micromotor-based fluorescence assays
    Yuan, K; de la Asuncion-Nadal, V; Cuntin-Abal, C; Jurado-Sanchez, B; Escarpa, A
  • Field evaluation of COVID-19 antigen tests versus RNA based detection: potential lower sensitivity compensated by immediate results, technical simplicity, and low cost
    Matsuda, EM; de Campos, IB; de Oliveira, IP; Colpas, DR; Carmo, A; Brigido, LFM
  • COVID-19 diagnosis-a review of current methods
    Yuce, M; Filiztekin, E; Ozkaya, KG
  • COVID-19 antibody tests and their limitations
    Liu, G; Rusling, JF
  • Understanding the influence factors in viral nucleic acid test of 2019 novel coronavirus (2019-nCoV)
    Mo, X; Qin, W; Fu, Q; Guan, M
  • Real-time RT-PCR in COVID-19 detection: issues affecting the results
    Tahamtan, A; Ardebili, A
  • Diagnostic salivary tests for SARS-CoV-2
    Azzi, L; Maurino, V; Baj, A; Dani, M; d’Aiuto, A; Fasano, M; Lualdi, M; Sessa, F; Alberio, T
  • Selective isolation of gold facilitated by second-sphere coordination with alpha-cyclodextrin
    Liu, Z; Frasconi, M; Lei, J; Brown, ZJ; Zhu, Z; Cao, D; Iehl, J; Liu, G; Fahrenbach, AC; Botros, YY; Farha, OK; Hupp, JT; Mirkin, CA; Fraser Stoddart, J
  • Waste not want not: life cycle implications of gold recovery and recycling from nanowaste
    Pati, P; McGinnis, S; Vikesland, PJ
  • Biodegradable polymeric materials: synthetic approach
    Panchal, SS; Vasava, DV
  • Biodegradable polymers
    Vroman, I; Tighzert, L
  • Highly transparent, stretchable, and self-healable ionogel for multifunctional sensors, triboelectric nanogenerator, and wearable fibrous electronics
    Sun, L; Huang, H; Ding, Q; Guo, Y; Sun, W; Wu, Z; Qin, M; Guan, Q; You, Z
  • Fiber-shaped supercapacitors: advanced strategies toward high-performances and multi-functions
    Yang, J; Li, X-L; Zhou, J-W; Wang, B; Cheng, J-L
  • Advanced functional fiber and smart textile
    Shi, Q; Sun, J; Hou, C; Li, Y; Zhang, Q; Wang, H
  • Recycling and chemical upcycling of waste disposable medical masks
    Chen, H; Dong, X; Zhao, Y; Wang, D
  • Progress and perspective of antiviral protective material
    Zhou, J; Hu, Z; Zabihi, F; Chen, Z; Zhu, M