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Comparative Phytochemical Profiling and Quantification of Mangiferin Content in Species of Salacia from Southern Western Ghats of India

Comparative Phytochemical Profiling and Quantification of Mangiferin Content in Species of... AbstractMany species of the genus Salacia L. are used in traditional Indian systems of medicines for their anti-diabetic potential. In this study, we carried out a comparative phytochemical evaluation of the roots of nine species of Salacia viz. S. agasthiamalana, S. beddomei, S. brunoniana, S. chinensis, S. fruticosa, S. gambleana, S. malabarica, S.oblonga and S. wayanadica, which are distributed in the Southern Western Ghats. Qualitative profiling showed the presence of different phytochemicals. Subsequently quantification of mangiferin, the prominent anti-diabetic molecule was carried out using HPLC in all these species. S. brunoniana (2.586 mg/g of dry root) showed maximum mangiferin content, followed by S. beddomei (2.195), S. chinensis (1.57), S. fruticosa (1.055), S. oblonga (0.305), S. agasthiamalana (0.086), S. malabarica (0.0296), S. gambleana (0.0218) and S. wayanadica (0.0005). The presence of mangiferin in S. agasthiamalana, S. beddomei, S. brunoniana, S. gambleana, S. malabarica and S. wayanadica, are reported for the first time. The study identified that S. brunoniana and S. beddomei could be the most promising raw material for anti-diabetic drug formulations based on mangiferin content. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Biologically Active Products from Nature Taylor & Francis

Comparative Phytochemical Profiling and Quantification of Mangiferin Content in Species of Salacia from Southern Western Ghats of India

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Comparative Phytochemical Profiling and Quantification of Mangiferin Content in Species of Salacia from Southern Western Ghats of India

Jayaraj, R.; Sasidharan, N.; Tom, Beenu; Muhammad, Anaz K.
Journal of Biologically Active Products from Nature , Volume 6 (3): 14 – May 3, 2016

Abstract

AbstractMany species of the genus Salacia L. are used in traditional Indian systems of medicines for their anti-diabetic potential. In this study, we carried out a comparative phytochemical evaluation of the roots of nine species of Salacia viz. S. agasthiamalana, S. beddomei, S. brunoniana, S. chinensis, S. fruticosa, S. gambleana, S. malabarica, S.oblonga and S. wayanadica, which are distributed in the Southern Western Ghats. Qualitative profiling showed the presence of different phytochemicals. Subsequently quantification of mangiferin, the prominent anti-diabetic molecule was carried out using HPLC in all these species. S. brunoniana (2.586 mg/g of dry root) showed maximum mangiferin content, followed by S. beddomei (2.195), S. chinensis (1.57), S. fruticosa (1.055), S. oblonga (0.305), S. agasthiamalana (0.086), S. malabarica (0.0296), S. gambleana (0.0218) and S. wayanadica (0.0005). The presence of mangiferin in S. agasthiamalana, S. beddomei, S. brunoniana, S. gambleana, S. malabarica and S. wayanadica, are reported for the first time. The study identified that S. brunoniana and S. beddomei could be the most promising raw material for anti-diabetic drug formulations based on mangiferin content.

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Publisher
Taylor & Francis
Copyright
© 2016, Har Krishan Bhalla & Sons
ISSN
2231-1874
eISSN
2231-1866
DOI
10.1080/22311866.2016.1227721
Publisher site
See Article on Publisher Site

Abstract

AbstractMany species of the genus Salacia L. are used in traditional Indian systems of medicines for their anti-diabetic potential. In this study, we carried out a comparative phytochemical evaluation of the roots of nine species of Salacia viz. S. agasthiamalana, S. beddomei, S. brunoniana, S. chinensis, S. fruticosa, S. gambleana, S. malabarica, S.oblonga and S. wayanadica, which are distributed in the Southern Western Ghats. Qualitative profiling showed the presence of different phytochemicals. Subsequently quantification of mangiferin, the prominent anti-diabetic molecule was carried out using HPLC in all these species. S. brunoniana (2.586 mg/g of dry root) showed maximum mangiferin content, followed by S. beddomei (2.195), S. chinensis (1.57), S. fruticosa (1.055), S. oblonga (0.305), S. agasthiamalana (0.086), S. malabarica (0.0296), S. gambleana (0.0218) and S. wayanadica (0.0005). The presence of mangiferin in S. agasthiamalana, S. beddomei, S. brunoniana, S. gambleana, S. malabarica and S. wayanadica, are reported for the first time. The study identified that S. brunoniana and S. beddomei could be the most promising raw material for anti-diabetic drug formulations based on mangiferin content.

Journal

Journal of Biologically Active Products from Nature – Taylor & Francis

Published: May 3, 2016

Keywords: Salacia; Mangiferin; HPLC; Phytochemical profiling; Western Ghats

References

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