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In vitro antioxidative activities of three marine oligosaccharides

In vitro antioxidative activities of three marine oligosaccharides The antioxidant activities of three marine oligosaccharides, alginate oligosaccharides (AOs), chitosan oligosaccharides (COs), and fucoidan oligosaccharides (FOs), were investigated in vitro by several antioxidant assays, including hydroxyl radical scavenging, superoxide radical scavenging, erythrocyte hemolysis inhibiting, metal chelating activities, and anti-lipid peroxidation. The results show that these oligosaccharides exhibited different activities in various assays. AOs had the highest scavenging hydroxyl radical activity than FOs and COs at all the tested amounts. COs had the highest scavenging superoxide radical and inhibiting erythrocyte hemolysis activity than AOs and FOs at all the tested amounts. In the assay of chelating Fe2+, COs and FOs indicated good chelation while AOs hardly had any activity. In the assay of anti-lipid peroxidation, only COs had significantly high antioxidant activity. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Natural Product Research [Part A and Part B] Taylor & Francis

In vitro antioxidative activities of three marine oligosaccharides

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References (46)

Publisher
Taylor & Francis
Copyright
Copyright Taylor & Francis Group, LLC
ISSN
1029-2349
eISSN
1478-6419
DOI
10.1080/14786410701371215
pmid
17613823
Publisher site
See Article on Publisher Site

Abstract

The antioxidant activities of three marine oligosaccharides, alginate oligosaccharides (AOs), chitosan oligosaccharides (COs), and fucoidan oligosaccharides (FOs), were investigated in vitro by several antioxidant assays, including hydroxyl radical scavenging, superoxide radical scavenging, erythrocyte hemolysis inhibiting, metal chelating activities, and anti-lipid peroxidation. The results show that these oligosaccharides exhibited different activities in various assays. AOs had the highest scavenging hydroxyl radical activity than FOs and COs at all the tested amounts. COs had the highest scavenging superoxide radical and inhibiting erythrocyte hemolysis activity than AOs and FOs at all the tested amounts. In the assay of chelating Fe2+, COs and FOs indicated good chelation while AOs hardly had any activity. In the assay of anti-lipid peroxidation, only COs had significantly high antioxidant activity.

Journal

Natural Product Research [Part A and Part B]Taylor & Francis

Published: Jun 1, 2007

Keywords: Alginate oligosaccharides; Chitosan oligosaccharides; Fucoidan oligosaccharides; Antioxidant activities; Free radicals; Lipid peroxidation

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