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Reference intervals for serum testosterone, SHBG, LH and FSH in males from the NORIP project

Reference intervals for serum testosterone, SHBG, LH and FSH in males from the NORIP project AbstractReference intervals were calculated for male testosterone, SHBG, FSH and LH in serum from 599 individuals in the NORIP study. At 30 years of age, reference limits were calculated to 10.4–32.6 nmol/L testosterone, 13.5–57.4 nmol/L SHBG, 1.93–9.7 IU/L LH and 1.5–10.3 IU/L FSH, at 50 years, 9.3–31.3 nmol/L (testosterone), 18.4–75.6 nmol/L (SHBG), 2.01–10.4 IU/L (LH) and 2.04–12.4 IU/L (FSH), and at 70 years 8.6 to 30.7 nmol/L (testosterone), 27.8–101 nmol/L (SHBG), 2.22–11.2 IU/L (LH) and 2.71–14.2 IU/L (FSH). All age-+related changes were statistically significant. Reference intervals were also calculated for indices derived from testosterone, SHBG and albumin. Free androgen index, simply the ratio between testosterone and SHBG, returned results differing from the other elaborate indices, and the study thus favors use of a more elaborate index such as calculated free testosterone (CFT). http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Scandinavian Journal of Clinical & Laboratory Investigation Taylor & Francis

Reference intervals for serum testosterone, SHBG, LH and FSH in males from the NORIP project

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References (50)

Publisher
Taylor & Francis
Copyright
© Informa UK Ltd
ISSN
1502-7686
eISSN
0036-5513
DOI
10.3109/00365510903380886
pmid
19929279
Publisher site
See Article on Publisher Site

Abstract

AbstractReference intervals were calculated for male testosterone, SHBG, FSH and LH in serum from 599 individuals in the NORIP study. At 30 years of age, reference limits were calculated to 10.4–32.6 nmol/L testosterone, 13.5–57.4 nmol/L SHBG, 1.93–9.7 IU/L LH and 1.5–10.3 IU/L FSH, at 50 years, 9.3–31.3 nmol/L (testosterone), 18.4–75.6 nmol/L (SHBG), 2.01–10.4 IU/L (LH) and 2.04–12.4 IU/L (FSH), and at 70 years 8.6 to 30.7 nmol/L (testosterone), 27.8–101 nmol/L (SHBG), 2.22–11.2 IU/L (LH) and 2.71–14.2 IU/L (FSH). All age-+related changes were statistically significant. Reference intervals were also calculated for indices derived from testosterone, SHBG and albumin. Free androgen index, simply the ratio between testosterone and SHBG, returned results differing from the other elaborate indices, and the study thus favors use of a more elaborate index such as calculated free testosterone (CFT).

Journal

Scandinavian Journal of Clinical & Laboratory InvestigationTaylor & Francis

Published: Jan 1, 2009

Keywords: Fertility hormones; hormones; reference levels; endocrinology

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