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Risk factors for etiology and prognosis of mantle cell lymphoma

Risk factors for etiology and prognosis of mantle cell lymphoma Non-Hodgkin lymphomas (NHLs) include any kind of lymphoma except Hodgkin's lymphoma. Mantle cell lymphoma (MCL) is a B-cell NHL and it accounts for about 6% of all NHL cases. Its epidemiologic and clinical features, as well as biomarkers, can differ from those of other NHL subtypes. This article first provides a very brief description of MCL's epidemiology and clinical features. For etiology and prognosis separately, we review clinical, environmental, and molecular risk factors that have been suggested in the literature. Among a large number of potential risk factors, only a few have been independently validated, and their clinical utilization has been limited. More data need to be accumulated and effectively analyzed before clinically useful risk factors can be identified and used for prevention, diagnosis, prediction of prognosis path, and treatment selection. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Expert Review of Hematology Taylor & Francis

Risk factors for etiology and prognosis of mantle cell lymphoma

Expert Review of Hematology , Volume 7 (2): 11 – Apr 1, 2014
11 pages

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References (104)

Publisher
Taylor & Francis
Copyright
© Informa UK, Ltd.
ISSN
1747-4094
eISSN
1747-4086
DOI
10.1586/17474086.2014.889561
pmid
24559208
Publisher site
See Article on Publisher Site

Abstract

Non-Hodgkin lymphomas (NHLs) include any kind of lymphoma except Hodgkin's lymphoma. Mantle cell lymphoma (MCL) is a B-cell NHL and it accounts for about 6% of all NHL cases. Its epidemiologic and clinical features, as well as biomarkers, can differ from those of other NHL subtypes. This article first provides a very brief description of MCL's epidemiology and clinical features. For etiology and prognosis separately, we review clinical, environmental, and molecular risk factors that have been suggested in the literature. Among a large number of potential risk factors, only a few have been independently validated, and their clinical utilization has been limited. More data need to be accumulated and effectively analyzed before clinically useful risk factors can be identified and used for prevention, diagnosis, prediction of prognosis path, and treatment selection.

Journal

Expert Review of HematologyTaylor & Francis

Published: Apr 1, 2014

Keywords: etiology; mantle cell lymphoma; prognosis; risk factors

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