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Ruan (2005)
Identification of a novel point mutation of mouse proto-oncogene c-kit through N-ethyl-N-nitrosourea mutagenesisGenetics, 169
A. Muro, M. Marro, S. Gajović, F. Porro, L. Luzzatto, F. Baralle (2000)
Mild spherocytic hereditary elliptocytosis and altered levels of α- and γ-adducins in β-adducin-deficient miceBlood, 95
A. Muro, M. Marro, S. Gajović, F. Porro, L. Luzzatto, F. Baralle (2000)
Mild spherocytic hereditary elliptocytosis and altered levels of alpha- and gamma-adducins in beta-adducin-deficient mice.Blood, 95 12
V. Gailus-Durner, H. Fuchs, T. Adler, Antonio Pimentel, L. Becker, I. Bolle, J. Calzada-Wack, C. Dalke, N. Ehrhardt, B. Ferwagner, W. Hans, S. Hölter, G. Hölzlwimmer, M. Horsch, A. Javaheri, M. Kallnik, E. Kling, C. Lengger, C. Mörth, I. Mossbrugger, B. Naton, C. Prehn, O. Puk, B. Rathkolb, J. Rozman, A. Schrewe, F. Thiele, J. Adamski, B. Aigner, H. Behrendt, D. Busch, J. Favor, J. Graw, G. Heldmaier, B. Ivandic, H. Katus, M. Klingenspor, T. Klopstock, E. Kremmer, M. Ollert, L. Quintanilla‐Martinez, H. Schulz, E. Wolf, W. Wurst, M. Angelis (2009)
Systemic first-line phenotyping.Methods in molecular biology, 530
E. Devlin, L. Dacosta, N. Mohandas, G. Elliott, D. Bodine (2010)
A transgenic mouse model demonstrates a dominant negative effect of a point mutation in the RPS19 gene associated with Diamond-Blackfan anemia.Blood, 116 15
D. Bishop, S. Clavero, N. Mohandas, R. Desnick (2011)
Congenital Erythropoietic Porphyria: Characterization of Murine Models of the Severe Common (C73R/C73R) and Later-Onset GenotypesMolecular Medicine, 17
H. Mok, A. Mlodnicka, M. Hentze, M. Muckenthaler, A. Schumacher (2006)
The Molecular Circuitry Regulating the Switch between Iron Deficiency and Overload in Mice*Journal of Biological Chemistry, 281
Ivan Barrantes, A. Montero-Pedrazuela, A. Guadaño-Ferraz, M. Obregon, R. Mena, V. Gailus-Durner, H. Fuchs, T. Franz, S. Kalaydjiev, M. Klempt, S. Hölter, B. Rathkolb, C. Reinhard, G. Escobar, J. Bernal, D. Busch, W. Wurst, E. Wolf, H. Schulz, S. Shtrom, E. Greiner, M. Angelis, H. Westphal, C. Niehrs (2006)
Generation and Characterization of dickkopf3 Mutant MiceMolecular and Cellular Biology, 26
J. Nemzek, G. Bolgos, B. Williams, D. Remick (2001)
Differences in normal values for murine white blood cell counts and other hematological parameters based on sampling siteInflammation Research, 50
Hilary Gates, A. Mallon, Steve Brown (2011)
High-throughput mouse phenotyping.Methods, 53 4
A. Shet, T. Hoffmann, M. Jiroušková, Christin Janczak, J. Stevens, A. Adamson, N. Mohandas, E. Manci, T. Cynober, B. Coller (2008)
Morphological and functional platelet abnormalities in Berkeley sickle cell mice.Blood cells, molecules & diseases, 41 1
Y. Tsuchiya, A. Watanabe, Nobuyoshi Fujisawa, T. Kaneko, T. Ishizu, Takanori Fujimoto, Kazutoshi Nakamura, Masaharu Yamamoto (2004)
Effects of desalted deep seawater on hematologic and blood chemical values in mice.The Tohoku journal of experimental medicine, 203 3
Hai-Bin Ruan, Nian-nian Zhang, Xiang Gao (2005)
Identification of a Novel Point Mutation of Mouse Proto-Oncogene c-kit Through N-Ethyl-N-nitrosourea Mutagenesis Sequence data from this article have been deposited with the EMBL/GenBank Data Libraries under accession nos. AY536430 and AY536431.Genetics, 169
V. Divoký, Z. Liu, T. Ryan, J. Prchal, T. Townes, J. Prchal (2001)
Mouse model of congenital polycythemia: Homologous replacement of murine gene by mutant human erythropoietin receptor gene.Proceedings of the National Academy of Sciences of the United States of America, 98 3
J. Seibel, K. Bodie, S. Weber, D. Bury, M. Kron, G. Blaich (2010)
Comparison of haematology, coagulation and clinical chemistry parameters in blood samples from the sublingual vein and vena cava in Sprague–Dawley ratsLaboratory Animals, 44
B. Hyun, G. Gulati, J. Ashton (1991)
Differential leukocyte count: manual or automated, what should it be?Yonsei medical journal, 32 4
Maike Heimann, D. Roth, D. Ledieu, Rudolf Pfister, W. Classen (2010)
Sublingual and submandibular blood collection in mice: a comparison of effects on body weight, food consumption and tissue damageLaboratory Animals, 44
M. Angelis, H. Flaswinkel, H. Fuchs, B. Rathkolb, D. Soewarto, S. Marschall, S. Heffner, W. Pargent, K. Wuensch, M. Jung, A. Reis, T. Richter, F. Alessandrini, T. Jakob, Edith Fuchs, H. Kolb, E. Kremmer, Karlheinz Schaeble, Boris Rollinski, A. Roscher, C. Peters, T. Meitinger, T. Strom, T. Steckler, F. Holsboer, T. Klopstock, F. Gekeler, C. Schindewolf, Thomas Jung, K. Avraham, H. Behrendt, J. Ring, A. Zimmer, K. Schughart, K. Pfeffer, E. Wolf, R. Balling (2000)
Genome-wide, large-scale production of mutant mice by ENU mutagenesisNature Genetics, 25
V. Gailus-Durner, H. Fuchs, L. Becker, I. Bolle, M. Brielmeier, J. Calzada-Wack, R. Elvert, N. Ehrhardt, C. Dalke, T. Franz, E. Grundner-Culemann, Stephan Hammelbacher, S. Hölter, G. Hölzlwimmer, M. Horsch, A. Javaheri, S. Kalaydjiev, M. Klempt, E. Kling, Sandra Kunder, C. Lengger, T. Lisse, T. Mijalski, B. Naton, V. Pedersen, C. Prehn, Gerhard Przemeck, I. Rácz, C. Reinhard, P. Reitmeir, Ilka Schneider, A. Schrewe, R. Steinkamp, C. Zybill, J. Adamski, J. Beckers, H. Behrendt, J. Favor, J. Graw, G. Heldmaier, H. Höfler, B. Ivandic, H. Katus, P. Kirchhof, M. Klingenspor, T. Klopstock, A. Lengeling, Werner Müller, F. Ohl, M. Ollert, L. Quintanilla‐Martinez, Jörg Schmidt, H. Schulz, E. Wolf, W. Wurst, A. Zimmer, D. Busch, M. Angelis (2005)
Introducing the German Mouse Clinic: open access platform for standardized phenotypingNature Methods, 2
S. Shin, C. Kamerath, J. Gilson, J. Leypoldt (2006)
Effects of anaesthesia on fluid and solute transport in a C57BL6 mouse model of peritoneal dialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 21 10
V. Haase (2006)
Hypoxia-inducible factors in the kidney.American journal of physiology. Renal physiology, 291 2
A. Simmons, P. Leaverton, G. Elbert (1974)
Normal laboratory values for differential white cell counts established by manual and automated cytochemical methods (Hemalog DTM)Journal of Clinical Pathology, 27
S. Rivera, T. Ganz (2009)
Animal models of anemia of inflammation.Seminars in hematology, 46 4
S. Christensen, L. Mikkelsen, J. Fels, T. Bodvarsdottir, A. Hansen (2009)
Quality of plasma sampled by different methods for multiple blood sampling in miceLaboratory Animals, 43
Divoky (2001)
Mouse model of congenital polycythemia: Homologous replacement of murine gene by mutant human erythropoietin receptor geneProc. Natl. Acad. Sci. U.S.A., 98
W. Golde, Peter Gollobin, Luis Rodriguez (2005)
A rapid, simple, and humane method for submandibular bleeding of mice using a lancetLab Animal, 34
M. Ameri, H. Schnaars, John Sibley, D. Honor (2011)
Stability of hematologic analytes in monkey, rabbit, rat, and mouse blood stored at 4°C in EDTA using the ADVIA 120 hematology analyzer.Veterinary clinical pathology, 40 2
H. Holmberg, M. Kiersgaard, L. Mikkelsen, M. Tranholm (2011)
Impact of blood sampling technique on blood quality and animal welfare in haemophilic miceLaboratory Animals, 45
Casey Doucette, C. Rosen (2014)
Current Protocols in Mouse Biology.Current protocols in mouse biology, 2014
B. Rathkolb, W. Hans, C. Prehn, H. Fuchs, V. Gailus-Durner, B. Aigner, J. Adamski, E. Wolf, M. Angelis (2013)
Clinical Chemistry and Other Laboratory Tests on Mouse Plasma or SerumCurrent Protocols in Mouse Biology, 3
John Donovan, Patricia Brown (2006)
Blood CollectionCurrent Protocols in Immunology, 73
I. Lilliehöök, H. Tvedten (2009)
Validation of the Sysmex XT-2000iV hematology system for dogs, cats, and horses. I. Erythrocytes, platelets, and total leukocyte counts.Veterinary clinical pathology, 38 2
C. Argmann, J. Auwerx (2006)
Collection of Blood and Plasma from the MouseCurrent Protocols in Molecular Biology, 75
Katsuya Tanaka, T. Kawano, T. Tomino, Hiroaki Kawano, Tsuyoshi Okada, S. Oshita, A. Takahashi, Y. Nakaya (2009)
Mechanisms of Impaired Glucose Tolerance and Insulin Secretion during Isoflurane AnesthesiaAnesthesiology, 111
Maja Spasic, J. Kiss, T. Herrmann, Regina Kessler, Jens Stolte, B. Galy, B. Rathkolb, E. Wolf, W. Stremmel, M. Hentze, M. Muckenthaler (2007)
Physiologic systemic iron metabolism in mice deficient for duodenal Hfe.Blood, 109 10
E. Wirth-Dzieciołowska, J. Karaszewska, K. Pyśniak, M. Smolinska, M. Gajewska (2009)
Selected peripheral blood cell parameters in twelve inbred strains of laboratory mice., 27
E. Rappaport, B. Helbert, R. Beissner, A. Trowbridge (1988)
Automated hematology: where we stand.Southern medical journal, 81 3
I. Fernandez, A. Peña, Nahia Teso, Virginia Pérez, Juan Rodríguez-Cuesta (2010)
Clinical biochemistry parameters in C57BL/6J mice after blood collection from the submandibular vein and retroorbital plexus.Journal of the American Association for Laboratory Animal Science : JAALAS, 49 2
Rosario González-Casas, E. Jones, R. Moreno-otero (2009)
Spectrum of anemia associated with chronic liver disease.World journal of gastroenterology, 15 37
F. Fernández-Bañares, Helena Monzón, M. Forné (2009)
A short review of malabsorption and anemia.World journal of gastroenterology, 15 37
M. Justice (2008)
Removing the cloak of invisibility: phenotyping the mouseDisease Models & Mechanisms, 1
John Donovan, Patricia Brown (2001)
UNIT 1.4 AnesthesiaCurrent protocols in immunology
S. Wakana, Tomohiro Suzuki, T. Furuse, Kimio Kobayashi, I. Miura, H. Kaneda, Ikuko Yamada, Hiromi Motegi, Hideaki Toki, Maki Inoue, O. Minowa, T. Noda, K. Waki, Nobuhiko Tanaka, H. Masuya, Y. Obata (2009)
Introduction to the Japan Mouse Clinic at the RIKEN BioResource Center.Experimental animals, 58 5
K. Aasland, E. Skjerve, A. Smith (2010)
Quality of blood samples from the saphenous vein compared with the tail vein during multiple blood sampling of miceLaboratory Animals, 44
B. Aigner, B. Rathkolb, M. Klempt, S. Wagner, Dian Michel, M. Klaften, J. Laufs, B. Schneider, R. Sedlmeier, M. Angelis, E. Wolf (2011)
Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parametersMammalian Genome, 22
I. Lilliehöök, H. Tvedten (2009)
Validation of the Sysmex XT-2000iV hematology system for dogs, cats, and horses. II. Differential leukocyte counts.Veterinary clinical pathology, 38 2
F. Xie, C. Bruntlett, Yongxin Zhu, C. Kissinger, P. Kissinger (2003)
Good Preclinical Bioanalytical Chemistry Requires Proper Sampling from Laboratory Animals: Automation of Blood and Microdialysis Sampling Improves the Productivity of LC/MSMS.Analytical Sciences, 19
R. Allison, J. Meinkoth (2007)
Hematology without the numbers: in-clinic blood film evaluation.The Veterinary clinics of North America. Small animal practice, 37 2
M. Nelson, A. Lamont (1961)
Haemoglobinometry by an automatic analytical procedureJournal of Clinical Pathology, 14
W. Goossens, L. Hove, R. Verwilghen (1991)
Monocyte counting: discrepancies in results obtained with different automated instruments.Journal of Clinical Pathology, 44
M. Nelson, J. Carville (1962)
Blood cell counting: A comparison of the E.E.L. and coulter machinesIrish Journal of Medical Science (1926-1967), 37
Donovan (1998)
AnesthesiaCurr. Protoc. Immunol., 27
B. Rathkolb, T. Decker, Edith Fuchs, D. Soewarto, C. Fella, S. Heffner, W. Pargent, R. Wanke, R. Balling, M. Angelis, H. Kolb, E. Wolf (2000)
The clinical-chemical screen in the Munich ENU Mouse Mutagenesis Project: screening for clinically relevant phenotypesMammalian Genome, 11
(1998)
For this blood collection method, we strongly recommend having two people working in tandem
J. Knoll, S. Rowell (1996)
Clinical hematology. In-clinic analysis, quality control, reference values, and system selection.The Veterinary clinics of North America. Small animal practice, 26 5
Basic phenotyping of inbred mouse strains and genetically modified mouse models usually includes the determination of blood‐based parameters as a diagnostic screen for genotype effects on metabolism and organ function. A broad range of analytes, including hematological parameters, can be reliably determined in mouse blood, if appropriate samples are available. Here we describe recommended techniques for blood collection from mice and the considerations that have to be taken into account to get adequate samples for hematological investigations. Furthermore, we describe established methods used in the German Mouse Clinic (GMC) to determine hematological parameters in the mouse. Curr. Protoc. Mouse Biol. 3:101‐119 © 2013 by John Wiley & Sons, Inc.
Current Protocols in Mouse Biology – Wiley
Published: Jun 1, 2013
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