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Clinical neurological abnormalities in young adults with Asperger syndrome

Clinical neurological abnormalities in young adults with Asperger syndrome Abstract  Children with Asperger syndrome (AS), a neurodevelopmental disorder falling in the autism spectrum disorders, have an increased rate of neurological abnormalities, especially in motor coordination. While AS is a lifelong condition, little is known about the persistence of neurological abnormalities in adulthood. Twenty young adults with AS were compared with 10 healthy controls using a structured clinical neurological rating scale. The score for neurological abnormalities was higher in the AS group. In addition, a subscore for neurological soft signs indicating defective functioning of the central nervous system with a non‐localizing value was significantly higher in the AS subjects. This preliminary study indicates that neurological abnormalities, soft signs in particular, represent a non‐specific vulnerability factor for AS. Consistent with other features of AS, neurological abnormalities seem to persist into adulthood. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychiatry and Clinical Neurosciences Wiley

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References (22)

Publisher
Wiley
Copyright
Copyright © 2006 Wiley Subscription Services
ISSN
1323-1316
eISSN
1440-1819
DOI
10.1111/j.1440-1819.2006.01494.x
pmid
16594952
Publisher site
See Article on Publisher Site

Abstract

Abstract  Children with Asperger syndrome (AS), a neurodevelopmental disorder falling in the autism spectrum disorders, have an increased rate of neurological abnormalities, especially in motor coordination. While AS is a lifelong condition, little is known about the persistence of neurological abnormalities in adulthood. Twenty young adults with AS were compared with 10 healthy controls using a structured clinical neurological rating scale. The score for neurological abnormalities was higher in the AS group. In addition, a subscore for neurological soft signs indicating defective functioning of the central nervous system with a non‐localizing value was significantly higher in the AS subjects. This preliminary study indicates that neurological abnormalities, soft signs in particular, represent a non‐specific vulnerability factor for AS. Consistent with other features of AS, neurological abnormalities seem to persist into adulthood.

Journal

Psychiatry and Clinical NeurosciencesWiley

Published: Jan 1, 2006

Keywords: ; ;

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