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Computer immunology

Computer immunology Summary:  This review describes a body of work on computational immune systems that behave analogously to the natural immune system. These artificial immune systems (AIS) simulate the behavior of the natural immune system and in some cases have been used to solve practical engineering problems such as computer security. AIS have several strengths that can complement wet lab immunology. It is easier to conduct simulation experiments and to vary experimental conditions, for example, to rule out hypotheses; it is easier to isolate a single mechanism to test hypotheses about how it functions; agent‐based models of the immune system can integrate data from several different experiments into a single in silico experimental system. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Immunological Reviews Wiley

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References (145)

Publisher
Wiley
Copyright
Copyright © 2007 Wiley Subscription Services
ISSN
0105-2896
eISSN
1600-065X
DOI
10.1111/j.1600-065X.2007.00499.x
pmid
17367343
Publisher site
See Article on Publisher Site

Abstract

Summary:  This review describes a body of work on computational immune systems that behave analogously to the natural immune system. These artificial immune systems (AIS) simulate the behavior of the natural immune system and in some cases have been used to solve practical engineering problems such as computer security. AIS have several strengths that can complement wet lab immunology. It is easier to conduct simulation experiments and to vary experimental conditions, for example, to rule out hypotheses; it is easier to isolate a single mechanism to test hypotheses about how it functions; agent‐based models of the immune system can integrate data from several different experiments into a single in silico experimental system.

Journal

Immunological ReviewsWiley

Published: Jan 1, 2007

Keywords: ; ; ;

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