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Myung Yoo, C. Yang, S. Kim, M. Park, J. Ahn, J. Chung, H. Park (2017)
Efficacy of steroid therapy based on symptomatic and functional improvement in patients with vestibular neuritis: a prospective randomized controlled trialEuropean Archives of Oto-Rhino-Laryngology, 274
S. Ohbayashi, M. Oda, Masahiko Yamamoto, M. Urano, K. Harada, Hidenori Horikoshi, H. Orihara, Chiaki Kitsuda (1993)
Recovery of the vestibular function after vestibular neuronitis.Acta oto-laryngologica. Supplementum, 503
J. Fishman, Chris Burgess, A. Waddell (2011)
Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis).The Cochrane database of systematic reviews, 5
G. Jacobson, C. Newman (1990)
The development of the Dizziness Handicap Inventory.Archives of otolaryngology--head & neck surgery, 116 4
Kai-Jing Leong, Timothy Lau, Vicky Stewart, E. Canetti (2021)
Systematic Review and Meta-analysis: Effectiveness of Corticosteroids in Treating Adults With Acute Vestibular NeuritisOtolaryngology–Head and Neck Surgery, 165
J. Edlow, Kiersten Gurley, D. Newman-Toker (2018)
A New Diagnostic Approach to the Adult Patient with Acute Dizziness.The Journal of emergency medicine, 54 4
F. Brusaferri, L. Candelise (2000)
Steroids for multiple sclerosis and optic neuritis: a meta-analysis of randomized controlled clinical trials.Journal of neurology, 247 6
T. Kitahara, K. Kondoh, T. Morihana, S. Okumura, A. Horii, N. Takeda, T. Kubo (2003)
Steroid effects on vestibular compensation in humanNeurological Research, 25
E. Ismail, A. Morgan, Akram Rahman (2019)
Corticosteroids versus vestibular rehabilitation in long-term outcomes in vestibular neuritisJournal of Vestibular Research, 28
M. Sampson, J. McGowan, E. Cogo, J. Grimshaw, D. Moher, C. Lefebvre (2009)
An evidence-based practice guideline for the peer review of electronic search strategies.Journal of clinical epidemiology, 62 9
G. Keijzers, L. Cullen, D. Egerton-Warburton, D. Fatovich (2018)
Don't just do something, stand there! The value and art of deliberate clinical inertiaEmergency Medicine Australasia, 30
M. Strupp, V. Zingler, V. Arbusow, Daniel Niklas, K. Maag, M. Dieterich, S. Bense, D. Theil, K. Jahn, T. Brandt (2004)
Methylprednisolone, valacyclovir, or the combination for vestibular neuritis.The New England journal of medicine, 351 4
E. Aromataris, R. Fernandez, C. Godfrey, C. Holly, H. Khalil, P. Tungpunkom (2015)
Summarizing systematic reviews: methodological development, conduct and reporting of an umbrella review approachInternational Journal of Evidence-Based Healthcare, 13
Guri Tokle, S. Mørkved, G. Bråthen, F. Goplen, Ø. Salvesen, Haakon Arnesen, B. Holmeslet, S. Nordahl, Kjersti Wilhelmsen (2019)
Efficacy of Vestibular Rehabilitation Following Acute Vestibular Neuritis: A Randomized Controlled Trial.Otology & Neurotology
H. Niedermeyer, G. Zahneisen, P. Luppa, R. Busch, W. Arnold (2003)
Cortisol Levels in the Human Perilymph after Intravenous Administration of PrednisoloneAudiology and Neurotology, 8
A. Garro, L. Nigrovic (2017)
Managing Peripheral Facial PalsyAnnals of Emergency Medicine, 71
Rachael Taylor, L. Mcgarvie, Nicole Reid, A. Young, G. Halmágyi, M. Welgampola (2016)
Vestibular neuritis affects both superior and inferior vestibular nervesNeurology, 87
Y. Zhang, E. Akl, H. Schünemann (2018)
Using systematic reviews in guideline development: The GRADE approachResearch Synthesis Methods, 10
Howard Balshem, M. Helfand, H. Schünemann, A. Oxman, R. Kunz, J. Brożek, G. Vist, Y. Falck-Ytter, J. Meerpohl, S. Norris, G. Guyatt (2011)
GRADE guidelines: 3. Rating the quality of evidence.Journal of clinical epidemiology, 64 4
Y. Okinaka, T. Sekitani, H. Okazaki, M. Miura, T. Tahara (1993)
Progress of caloric response of vestibular neuronitis.Acta oto-laryngologica. Supplementum, 503
M. Karlberg, M. Magnusson (2011)
Treatment of Acute Vestibular Neuronitis With GlucocorticoidsOtology & Neurotology, 32
Richard Baron, K. Steenerson, Jennifer Alyono (2021)
Acute Vestibular Syndrome and ER Presentations of Dizziness.Otolaryngologic clinics of North America
Julia Sjögren, M. Magnusson, F. Tjernström, M. Karlberg (2019)
Steroids for Acute Vestibular Neuronitis—the Earlier the Treatment, the Better the Outcome?Otology & Neurotology, 40
A. Shupak, A. Issa, A. Golz, M. Kaminer, I. Braverman (2008)
Prednisone Treatment for Vestibular NeuritisOtology & Neurotology, 29
B. Shea, Barnaby Reeves, George Wells, Micere Thuku, Candyce Hamel, Julian Moran, David Moher, P. Tugwell, Vivian Welch, Elizabeth Kristjansson, David Henry (2017)
AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or bothThe BMJ, 358
Ángel Batuecas-Caletrío, Raquel Yáñez-González, Carmen Sánchez-Blanco, P. Pérez, E. González-Sánchez, L. Sánchez, D. Kaski (2015)
Glucocorticoids improve acute dizziness symptoms following acute unilateral vestibulopathyJournal of Neurology, 262
Laurence Ariyasu, F. Byl, Monroe Sprague, K. Adour (1990)
The beneficial effect of methylprednisolone in acute vestibular vertigo.Archives of otolaryngology--head & neck surgery, 116 6
S. Chandrasekhar, R. Rubinstein, J. Kwartler, Michael Gatz, Patricia Connelly, Elizabeth Huang, S. Baredes (2000)
Dexamethasone pharmacokinetics in the inner ear: comparison of route of administration and use of facilitating agents.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 122 4
M. Engström, T. Berg, A. Stjernquist‐Desatnik, S. Axelsson, A. Pitkäranta, M. Hultcrantz, M. Kanerva, P. Hanner, L. Jonsson (2008)
Prednisolone and valaciclovir in Bell's palsy: a randomised, double-blind, placebo-controlled, multicentre trialThe Lancet Neurology, 7
J. Goudakos, K. Markou, G. Psillas, V. Vital, M. Tsaligopoulos (2014)
Corticosteroids and vestibular exercises in vestibular neuritis. Single-blind randomized clinical trial.JAMA otolaryngology-- head & neck surgery, 140 5
Ji Kim, W. Cha, D. Chang, Ho Lee (2015)
The Effect of Intravenous Dexamethasone on the Nausea Accompanying Vestibular Neuritis: A Preliminary Study.Clinical therapeutics, 37 11
40026386 Undeliverable (2009)
Canadian Agency for Drugs and Technologies in Health
V. Smith, D. Devane, C. Begley, M. Clarke (2011)
Methodology in conducting a systematic review of systematic reviews of healthcare interventionsBMC Medical Research Methodology, 11
J. Goudakos, K. Markou, V. Franco-Vidal, V. Vital, M. Tsaligopoulos, V. Darrouzet (2010)
Corticosteroids in the Treatment of Vestibular Neuritis: A Systematic Review and Meta-AnalysisOtology & Neurotology, 31
J. Bergenius, O. Perols (1999)
Vestibular neuritis: a follow-up study.Acta oto-laryngologica, 119 8
G. Guyatt, A. Oxman, N. Santesso, M. Helfand, G. Vist, R. Kunz, J. Brożek, S. Norris, J. Meerpohl, B. Djulbegovic, P. Alonso-Coello, Piet Post, J. Busse, P. Glasziou, R. Christensen, H. Schünemann (2013)
GRADE guidelines: 12. Preparing summary of findings tables-binary outcomes.Journal of clinical epidemiology, 66 2
I. Wegner, P. Benthem, M. Aarts, T. Bruintjes, W. Grolman, G. Heijden (2012)
Insufficient Evidence for the Effect of Corticosteroid Treatment on Recovery of Vestibular NeuritisOtolaryngology–Head and Neck Surgery, 147
R. Baloh (2003)
Clinical practice. Vestibular neuritis.The New England journal of medicine, 348 11
J. Edlow (2017)
Diagnosing Patients With Acute-Onset Persistent Dizziness.Annals of emergency medicine, 71 5
G. Guyatt, K. Thorlund, A. Oxman, S. Walter, D. Patrick, T. Furukawa, B. Johnston, P. Karanicolas, E. Akl, G. Vist, R. Kunz, J. Brożek, L. Kupper, Sandra Martin, J. Meerpohl, P. Alonso-Coello, R. Christensen, H. Schunemann (2013)
GRADE guidelines: 13. Preparing summary of findings tables and evidence profiles-continuous outcomes.Journal of clinical epidemiology, 66 2
S. Hegemann, A. Wenzel (2017)
Diagnosis and Treatment of Vestibular Neuritis/Neuronitis or Peripheral Vestibulopathy (PVP)? Open Questions and Possible Answers.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 38 5
N. Wilczynski, D. Morgan (2004)
Optimal search strategies for retrieving systematic reviews from Medline: analytical surveyBMJ : British Medical Journal, 330
G. Guyatt, A. Oxman, E. Akl, R. Kunz, G. Vist, J. Brożek, S. Norris, Y. Falck-Ytter, P. Glasziou, H. DeBeer, Roman Jaeschke, D. Rind, J. Meerpohl, P. Dahm, H. Schünemann (2011)
GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables.Journal of clinical epidemiology, 64 4
Gaeun Kim, Jae-Hyun Seo, Seung Lee, Dong-Hee Lee (2021)
Therapeutic effect of steroids on vestibular neuritis: Systematic review and meta‐analysisClinical Otolaryngology, 47
F. Godemann, F. Godemann, K. Siefert, M. Hantschke-Brüggemann, P. Neu, R. Seidl, A. Ströhle (2005)
What accounts for vertigo one year after neuritis vestibularis - anxiety or a dysfunctional vestibular organ?Journal of psychiatric research, 39 5
I. Adamec, M. Skorić, T. Gabelić, B. Barun, J. Ljevak, Andreja Kovač, I. Jurjević, M. Habek (2015)
Intravenous dexamethasone in acute management of vestibular neuritis: a randomized, placebo-controlled, single-blind trialEuropean Journal of Emergency Medicine, 23
Luke Chen, W. Lee, B. Chambers, H. Dewey (2011)
Diagnostic accuracy of acute vestibular syndrome at the bedside in a stroke unitJournal of Neurology, 258
S. Carmona, C. Martínez, G. Zalazar, M. Moro, Ángel Batuecas-Caletrío, L. Luís, C. Gordon (2016)
The Diagnostic Accuracy of Truncal Ataxia and HINTS as Cardinal Signs for Acute Vestibular SyndromeFrontiers in Neurology, 7
A. Rezaie, F. Hashemian, N. Rezaie (2006)
CORTICOSTEROIDS EFFECT ON VESTIBULAR NEURITIS SYMPTOM RELIEF
INTRODUCTIONVestibular neuritis (VN) is an acute peripheral vestibulopathy presumably caused by a viral or postviral inflammation of the vestibular component of the eighth cranial nerve that presents as an acute vestibular syndrome.1 When the cochlear component is also involved, it is called labyrinthitis and hearing is also affected in those cases. Posterior circulation stroke, adverse medication effects, and infections can present similarly, but VN is the most common etiology of acute vestibular syndrome persisting for more than 24 h and presenting to the emergency department (ED).2 Clinically, the most common presentation of VN is a sudden onset of sustained vertigo and imbalance accompanied by acute spontaneous unidirectional horizontal nystagmus with a slight torsional component that is suppressed with visual fixation. These patients have a positive head impulse test (presence of a corrective saccade), no skew deviation, and gait instability but usually with preserved ability to ambulate unassisted.3,4 Autonomic features such as nausea and vomiting may also be present.Leaving aside the diagnostic dilemma of differentiating VN from posterior stroke among patients presenting with acute vestibular syndrome,5,6 those with a presumed diagnosis of VN require acute disease‐specific treatment and a short course of corticosteroids is among the management strategies considered by specialists.7
Academic Emergency Medicine – Wiley
Published: May 1, 2023
Keywords: Caloric test; corticosteroids; dexamethasone; dizziness; head impulse test; methylprednisolone; nausea; Steroid; vertigo; vestibular neuritis; vestibular rehabilitation
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