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Does selective inhibition training reduce relapse rates when added to standard treatment of alcohol use disorder? A randomized controlled trial

Does selective inhibition training reduce relapse rates when added to standard treatment of... INTRODUCTIONAlcohol use disorder (AUD) ranks among the most prevalent psychiatric disorders globally (World Health Organization [WHO], 2018), with high mortality rates (Schwarzinger et al., 2017), considerable disability and tremendous societal costs (Carvalho et al., 2019). Furthermore, despite continuous efforts to improve treatment of this disorder, relapse rates typically exceed 50% in the first year after treatment (e.g., Cutler & Fishbain, 2005).As AUD develops, cue‐elicited action tendencies become more important in determining behavior. The processing of incoming information, and consequently, the behavioral tendencies become biased toward addictive substances (Bechara, 2005; Stacy & Wiers, 2010; Verdejo‐Garcia & Albein‐Urios, 2021). This leads to an imbalance between strong impulsive reactions toward drug‐related cues, along with relatively weak control over these impulses (Bechara, 2005; Wiers et al., 2007). The influence of biased cognitive processes on the maintenance of mental disorders, including addictions, is highlighted by cognitive models (MacLeod & Mathews, 2012; Wiers et al., 2013). To reduce the detrimental influences of cognitive biases on mental health, a new form of translational intervention was developed, collectively called cognitive bias modification (CBM; Wiers et al., 2013). Over the past decade, varieties of cognitive training, all using the principles of CBM, have effectively reduced relapse rates after 1 year by approximately 10% (Eberl et al., 2013; Salemink et al., 2021; Wiers et http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Alcoholism Wiley

Does selective inhibition training reduce relapse rates when added to standard treatment of alcohol use disorder? A randomized controlled trial

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Publisher
Wiley
Copyright
© 2023 by the Research Society on Alcoholism
ISSN
0145-6008
eISSN
1530-0277
DOI
10.1111/acer.15055
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Abstract

INTRODUCTIONAlcohol use disorder (AUD) ranks among the most prevalent psychiatric disorders globally (World Health Organization [WHO], 2018), with high mortality rates (Schwarzinger et al., 2017), considerable disability and tremendous societal costs (Carvalho et al., 2019). Furthermore, despite continuous efforts to improve treatment of this disorder, relapse rates typically exceed 50% in the first year after treatment (e.g., Cutler & Fishbain, 2005).As AUD develops, cue‐elicited action tendencies become more important in determining behavior. The processing of incoming information, and consequently, the behavioral tendencies become biased toward addictive substances (Bechara, 2005; Stacy & Wiers, 2010; Verdejo‐Garcia & Albein‐Urios, 2021). This leads to an imbalance between strong impulsive reactions toward drug‐related cues, along with relatively weak control over these impulses (Bechara, 2005; Wiers et al., 2007). The influence of biased cognitive processes on the maintenance of mental disorders, including addictions, is highlighted by cognitive models (MacLeod & Mathews, 2012; Wiers et al., 2013). To reduce the detrimental influences of cognitive biases on mental health, a new form of translational intervention was developed, collectively called cognitive bias modification (CBM; Wiers et al., 2013). Over the past decade, varieties of cognitive training, all using the principles of CBM, have effectively reduced relapse rates after 1 year by approximately 10% (Eberl et al., 2013; Salemink et al., 2021; Wiers et

Journal

Alcoholism – Wiley

Published: Mar 14, 2023

Keywords: alcohol approach bias; cognitive bias modification; evaluation; relapse prevention; selective inhibition training

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