Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Epigenetic priming as a mechanism of predetermination of spermatogonial stem cell fate

Epigenetic priming as a mechanism of predetermination of spermatogonial stem cell fate INTRODUCTIONMale germ cell development: Mammalian development involves propagation of cells from the zygote followed by cellular differentiation to form different germ layers, tissues, and organs in the embryo and fetus. This includes the formation of all somatic cell types and tissues, as well as the specification of the germ line. In mammals, the germ line is the first individual cell lineage allocated as such in the embryo proper. Indeed, the development of the male germ cell lineage is very well characterized—from the initial appearance of primordial germ cells (PGCs) at the egg cylinder stage of the early post‐implantation embryo to the ultimate development of mature spermatozoa in the post‐pubertal male—spanning at least 26 different spermatogenic cell types (Figure 1).1 Development of this lineage is largely progressive with all male PGCs becoming prospermatogonia (or dying). This includes the formation of mitotically active M prospermatogonia, which then transition to mitotically quiescent T1 prospermatogonia that then give rise to mitotically active T2 prospermatogonia.1 Prospermatogonia then give rise to spermatogonia (or die), and most spermatogonia give rise to spermatocytes (or die). The spermatocytes progress through meioses I and II to give rise to postmeiotic haploid spermatids that then differentiate into spermatozoa via spermiogenesis with http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Andrology Wiley

Epigenetic priming as a mechanism of predetermination of spermatogonial stem cell fate

McCarrey, John R.
Andrology , Volume 11 (5) – Jul 1, 2023
Download PDF
9 pages

Loading next page...
 
/lp/wiley/epigenetic-priming-as-a-mechanism-of-predetermination-of-gbP0nE7IGi
Publisher
Wiley
Copyright
© 2023 American Society of Andrology and European Academy of Andrology.
ISSN
2047-2919
eISSN
2047-2927
DOI
10.1111/andr.13332
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONMale germ cell development: Mammalian development involves propagation of cells from the zygote followed by cellular differentiation to form different germ layers, tissues, and organs in the embryo and fetus. This includes the formation of all somatic cell types and tissues, as well as the specification of the germ line. In mammals, the germ line is the first individual cell lineage allocated as such in the embryo proper. Indeed, the development of the male germ cell lineage is very well characterized—from the initial appearance of primordial germ cells (PGCs) at the egg cylinder stage of the early post‐implantation embryo to the ultimate development of mature spermatozoa in the post‐pubertal male—spanning at least 26 different spermatogenic cell types (Figure 1).1 Development of this lineage is largely progressive with all male PGCs becoming prospermatogonia (or dying). This includes the formation of mitotically active M prospermatogonia, which then transition to mitotically quiescent T1 prospermatogonia that then give rise to mitotically active T2 prospermatogonia.1 Prospermatogonia then give rise to spermatogonia (or die), and most spermatogonia give rise to spermatocytes (or die). The spermatocytes progress through meioses I and II to give rise to postmeiotic haploid spermatids that then differentiate into spermatozoa via spermiogenesis with

Journal

Andrology – Wiley

Published: Jul 1, 2023

Keywords: cell fate; epigenetic priming; prospermatogonia; spermatogenesis; spermatogonial stem cells

References

  • Toward a more precise and informative nomenclature describing fetal and neonatal male germ cells in rodents
    McCarrey, JR
  • The Biology of Mammalian Spermatogonia
    McCarrey, JR
  • The nature and dynamics of spermatogonial stem cells
    Rooij, DG
  • A comparative study of daily sperm production and testicular composition in humans and rats
    Johnson, L; Petty, CS; Neaves, WB
  • Further evidence for the proposed way of spermatogonial stem cell renewal in the rat and the mouse
    Rooij, DG
  • Spermatogonial stem cell renewal in the mouse. I. Normal situation
    Rooij, DG
  • The spermatogonial stem cell population in adult rats
    Huckins, C
  • Spermatogonial stem‐cell renewal in the mouse
    Oakberg, EF
  • Functional identification of the actual and potential stem cell compartments in mouse spermatogenesis
    Nakagawa, T; Nabeshima, Y; Yoshida, S
  • Functional hierarchy and reversibility within the murine spermatogenic stem cell compartment
    Nakagawa, T; Sharma, M; Nabeshima, Y; Braun, RE; Yoshida, S
  • Mouse spermatogenic stem cells continually interconvert between equipotent singly isolated and syncytial states
    Hara, K; Nakagawa, T; Enomoto, H; Suzuki, M; Yamamoto, M; Yoshida, S
  • A revised Asingle model to explain stem cell dynamics in the mouse male germline
    Lord, T; Oatley, JM
  • Purification of GFRα1+ and GFRα1‐ spermatogonial stem cells reveals a niche‐dependent mechanism for fate determination
    Garbuzov, A; Pech, MF; Hasegawa, K
  • Spermatogonial stem cells
    Kubota, H; Brinster, RL
  • A comparison between the morphology and cell kinetics of gonocytes and adult type undifferentiated spermatogonia in the mouse
    Kluin, PM; Rooij, DG
  • Gonocytes‐to‐spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling
    Pui, HP; Saga, Y
  • Developmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage
    Law, NC; Oatley, MJ; Oatley, JM
  • Transcriptional and translational heterogeneity among neonatal mouse spermatogonia
    Hermann, BP; Mutoji, KN; Velte, EK
  • The mammalian spermatogenesis single‐cell transcriptome, from spermatogonial stem cells to spermatids
    Hermann, BP; Cheng, K; Singh, A
  • Unique epigenetic programming distinguishes regenerative spermatogonial stem cells in the developing mouse testis
    Cheng, K; Chen, IC; Cheng, CE
  • Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis
    Yoshida, S; Takakura, A; Ohbo, K
  • The first round of mouse spermatogenesis is a distinctive program that lacks the self‐renewing spermatogonia stage
    Yoshida, S; Sukeno, M; Nakagawa, T
  • Functional and molecular features of the Id4+ germline stem cell population in mouse testes
    Chan, F; Oatley, MJ; Kaucher, AV
  • Id4 marks spermatogonial stem cells in the mouse testis
    Sun, F; Xu, Q; Zhao, D; Degui Chen, C
  • ID4 levels dictate the stem cell state in mouse spermatogonia
    Helsel, AR
  • Enhanced genetic integrity in mouse germ cells
    Murphey, P; McLean, DJ; McMahan, CA
  • Mutation frequency declines during spermatogenesis in young mice but increases in old mice
    Walter, CA; Intano, GW; McCarrey, JR
  • Germline genomes: a biological fountain of youth?
    Walter, CA; Walter, RB; McCarrey, JR
  • Pluripotent cells display enhanced resistance to mutagenesis
    Cooper, DJ; Chen, IC; Hernandez, C
  • Co‐regulation of pluripotency and genetic integrity at the genomic level
    Cooper, DJ; Walter, CA; McCarrey, JR
  • RNA sequencing: the teenage years
    Stark, R; Grzelak, M; Hadfield, J
  • Epigenetic priming in neurodevelopmental disorders
    Ernst, C; Jefri, M
  • Epigenetic priming in cancer initiation
    Vicente‐Dueñas, C; Hauer, J; Cobaleda, C; Borkhardt, A; Sánchez‐García, I
  • Epigenetic priming in immunodeficiencies
    Martínez‐Cano, J; Campos‐Sánchez, E; Cobaleda, C
  • An atlas of gene expression and gene co‐regulation in the human retina
    Pinelli, M; Carissimo, A; Cutillo, L
  • Transcriptional co‐expression and co‐regulation of genes coding for components of the oxidative phosphorylation system
    Waveren, C; Moraes, CT
  • Epigenetic priming by Dppa2 and 4 in pluripotency facilitates multi‐lineage commitment
    Eckersley‐Maslin, MA; Parry, A; Blotenburg, M
  • Epigenetic priming of enhancers predicts developmental competence of hESC‐derived endodermal lineage intermediates
    Wang, A; Yue, F; Li, Y
  • Organizational principles of 3D genome architecture
    Rowley, MJ; Corces, VG
  • Pioneer transcription factors initiating gene network changes
    Zaret, KS
  • Molecular mechanisms directing PRC2 recruitment and H3K27 methylation
    Laugesen, A; Højfeldt, JW; Helin, K
  • Transcription factors: from enhancer binding to developmental control
    Spitz, F; Furlong, EE
  • Transcriptional regulators dictate innate lymphoid cell fates
    Zhong, C; Zhu, J
  • A comparison of in vivo and in vitro DNA‐binding specificities suggests a new model for homeoprotein DNA binding in Drosophila embryos
    Carr, A; Biggin, MD
  • Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells
    Yang, A; Zhu, Z; Kapranov, P
  • A deep generative model for multi‐view profiling of single‐cell RNA‐seq and ATAC‐seq data
    Li, G; Fu, S; Wang, S
  • Joint profiling of histone modifications and transcriptome in single cells from mouse brain
    Zhu, C; Zhang, Y; Li, YE
  • Joint profiling of DNA methylation and chromatin architecture in single cells
    Li, G; Liu, Y; Zhang, Y