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Novel anticoagulants and antiplatelet agents; a guide for the urologist

Novel anticoagulants and antiplatelet agents; a guide for the urologist Novel oral anti‐coagulants (NOACs) are increasingly being used in clinical practice and are set to almost entirely replace the vitamin K antagonists, such as warfarin, in the near future. Similarly, new antiplatelet agents are now regularly used in place of older agents, such as aspirin and clopidogrel. In an ageing population, with an increasing burden of complex comorbidities, urologists will frequently encounter patients who will be using such agents. Some background knowledge, and an understanding, of these drugs and the issues that surround their usage, is essential. The present article will provide readers with an understanding of these new drugs, including their mechanisms of action, the up‐to‐date evidence justifying their recent introduction into clinical practice and the appropriate interval for stopping them before surgery. It will also consider the risks of perioperative bleeding for patients taking these drugs and the risks of venous thromboembolism in those in whom they are stopped. Strategies to manage anticoagulant‐associated bleeding are discussed. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png BJU International Wiley

Novel anticoagulants and antiplatelet agents; a guide for the urologist

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References (56)

Publisher
Wiley
Copyright
BJUI © 2015 BJU International
ISSN
1464-4096
eISSN
1464-410X
DOI
10.1111/bju.13131
pmid
25808010
Publisher site
See Article on Publisher Site

Abstract

Novel oral anti‐coagulants (NOACs) are increasingly being used in clinical practice and are set to almost entirely replace the vitamin K antagonists, such as warfarin, in the near future. Similarly, new antiplatelet agents are now regularly used in place of older agents, such as aspirin and clopidogrel. In an ageing population, with an increasing burden of complex comorbidities, urologists will frequently encounter patients who will be using such agents. Some background knowledge, and an understanding, of these drugs and the issues that surround their usage, is essential. The present article will provide readers with an understanding of these new drugs, including their mechanisms of action, the up‐to‐date evidence justifying their recent introduction into clinical practice and the appropriate interval for stopping them before surgery. It will also consider the risks of perioperative bleeding for patients taking these drugs and the risks of venous thromboembolism in those in whom they are stopped. Strategies to manage anticoagulant‐associated bleeding are discussed.

Journal

BJU InternationalWiley

Published: Nov 1, 2015

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