Access the full text.
Sign up today, get DeepDyve free for 14 days.
B. Abolpour, Ramtin Hekmatkhah, R. Shamsoddini (2022)
Optimum design for the Tesla micromixerMicrofluidics and Nanofluidics, 26
A. Díez, Francisca Moreira, Belisa Marinho, Jonathan Espíndola, L. Paulista, M. Sanromán, M. Pazos, R. Boaventura, V. Vilar (2018)
A step forward in heterogeneous photocatalysis: Process intensification by using a static mixer as catalyst supportChemical Engineering Journal
R. Karimi, S. Rezazadeh, M. Raad (2021)
Investigation of different geometrical configurations effect on mixing performance of passive split-and-recombine micromixerMicrofluidics and Nanofluidics, 25
Wasim Raza, Shakhawat Hossain, Kwang‐Yong Kim (2020)
A Review of Passive Micromixers with a Comparative AnalysisMicromachines, 11
H. Santana, J. Silva, Deborah Tortola, O. Taranto (2017)
Transesterification of sunflower oil in microchannels with circular obstructionsChinese Journal of Chemical Engineering, 26
Chen Z. (2020)
10.1039/D0LC00092BLab Chip, 20
Chen H. (2018)
10.1039/C8NR06367BNanoscale, 10
Enders A. (2019)
10.1002/smll.201804326Small, 15
Robert Channon, Ruth Menger, W. Wang, D. Carrão, Sravanthi Vallabhuneni, A. Kota, C. Henry (2021)
Design and application of a self-pumping microfluidic staggered herringbone mixerMicrofluidics and Nanofluidics, 25
G. Jeong, Seok Chung, Chang-beom Kim, Sang‐Hoon Lee (2010)
Applications of micromixing technology.The Analyst, 135 3
Lim T. W. (2011)
10.1039/C005325MLab Chip, 11
You J. B. (2015)
10.1039/C5LC00070JLab Chip, 15
Shaofei Shen, L. Kou, Xuan Zhang, Defu Wang, Y. Niu, Jinyi Wang (2018)
Regulating Secondary Flow in Ultra‐Low Aspect Ratio Microchannels by Dimensional ConfinementAdvanced Theory and Simulations, 1
(2011)
inMicrofluidics: Technologies and Applications
Brian Hama, Gautam Mahajan, P. Fodor, Miron Kaufman, C. Kothapalli (2018)
Evolution of mixing in a microfluidic reverse-staggered herringbone micromixerMicrofluidics and Nanofluidics, 22
Shakhawat Hossain, Insu Lee, S. Kim, Kwang‐Yong Kim (2017)
A micromixer with two-layer serpentine crossing channels having excellent mixing performance at low Reynolds numbersChemical Engineering Journal, 327
Keyin Liu, Qing Yang, Shengguan He, Feng Chen, Yulong Zhao, Xiaole Fan, Lei Li, Chao Shan, H. Bian (2013)
A high-efficiency three-dimensional helical micromixer in fused silicaMicrosystem Technologies, 19
Hyun‐Seob Song, S. Han (2005)
A general correlation for pressure drop in a Kenics static mixerChemical Engineering Science, 60
H. Xia, S. Wan, C. Shu, Y. Chew (2005)
Chaotic micromixers using two-layer crossing channels to exhibit fast mixing at low Reynolds numbers.Lab on a chip, 5 7
Bo Liu, Jiangang Zhao, J. Qian (2017)
Numerical analysis of cavitation erosion and particle erosion in butterfly valveEngineering Failure Analysis, 80
Petkovic K. (2016)
10.1039/C6LC01263ALab Chip, 17
Gaozhe Cai, Li Xue, Huilin Zhang, Jianhan Lin (2017)
A Review on MicromixersMicromachines, 8
N. Nguyen, Xiao-Yang Huang (2005)
An analytical model for mixing based on time-interleaved sequential segmentationMicrofluidics and Nanofluidics, 1
Baggie Nyande, K Thomas, R. Lakerveld (2021)
CFD Analysis of a Kenics Static Mixer with a Low Pressure Drop under Laminar Flow ConditionsIndustrial & Engineering Chemistry Research
A. Mariotti, C. Galletti, M. Salvetti, E. Brunazzi (2019)
Unsteady Flow Regimes in a T-Shaped Micromixer: Mixing and Characteristic FrequenciesIndustrial & Engineering Chemistry Research
Brody J. P. (1996)
10.1016/S0006-3495(96)79538-3Biophys. J., 71
S. Camarri, A. Mariotti, C. Galletti, E. Brunazzi, R. Mauri, M. Salvetti (2020)
An Overview of Flow Features and Mixing in Micro T and Arrow MixersIndustrial & Engineering Chemistry Research, 59
Capretto L. (2011)
10.1007/128_2011_150
Bo Liu, Chuanwen Lv, Chaozhan Chen, Bin Ran, M. Lan, Huaying Chen, Yonggang Zhu (2020)
Electrochemical Performance of Micropillar Array Electrodes in MicroflowsMicromachines, 11
M. Rafeie, M. Welleweerd, Amin Hassanzadeh-Barforoushi, M. Asadnia, W. Olthuis, Majid Warkiani (2017)
An easily fabricated three-dimensional threaded lemniscate-shaped micromixer for a wide range of flow rates.Biomicrofluidics, 11 1
A. Yang, Feng-Chao Chuang, C. Chen, Mei-Hui Lee, S. Chen, Tsai-Lung Su, Yung-Chun Yang (2015)
A high-performance micromixer using three-dimensional Tesla structures for bio-applicationsChemical Engineering Journal, 263
Ying Li, Chao Liu, Xiaojun Feng, Youzhi Xu, Bifeng Liu (2014)
Ultrafast microfluidic mixer for tracking the early folding kinetics of human telomere G-quadruplex.Analytical chemistry, 86 9
(1977)
in Proceedings of the Second European Conference on Mixing
Chenguang Zhang, Abigail Ferrell, K. Nandakumar (2019)
Study of a toroidal-helical pipe as an innovative static mixer in laminar flowsChemical Engineering Journal
Chia-Yen Lee, C. Chang, Y. Wang, L. Fu (2011)
Microfluidic Mixing: A ReviewInternational Journal of Molecular Sciences, 12
G. Xia, Jian Li, Xinping Tian, Mingzheng Zhou (2012)
Analysis of Flow and Mixing Characteristics of Planar Asymmetric Split-and-Recombine (P-SAR) Micromixers with Fan-Shaped CavitiesIndustrial & Engineering Chemistry Research, 51
Liu B. (2022)
10.1039/D2RE00103AReact. Chem. Eng., 7
T. Scherr, Christian Quitadamo, Preston Tesvich, D. Park, T. Tiersch, D. Hayes, Jin-Woo Choi, K. Nandakumar, W. Monroe (2012)
A planar microfluidic mixer based on logarithmic spiralsJournal of Micromechanics and Microengineering, 22
J. Knoška, L. Adriano, S. Awel, K. Beyerlein, O. Yefanov, D. Oberthuer, Gisel Murillo, N. Roth, I. Sarrou, P. Villanueva-Perez, M. Wiedorn, F. Wilde, S. Bajt, H. Chapman, M. Heymann (2020)
Ultracompact 3D microfluidics for time-resolved structural biologyNature Communications, 11
Camila Camargo, L. Shiroma, G. Giordano, A. Gobbi, L. Vieira, R. Lima (2016)
Turbulence in microfluidics: Cleanroom-free, fast, solventless, and bondless fabrication and application in high throughput liquid-liquid extraction.Analytica chimica acta, 940
O. Mihailova, Victor Lim, M. McCarthy, K. McCarthy, S. Bakalis (2015)
Laminar mixing in a SMX static mixer evaluated by positron emission particle tracking (PEPT) and magnetic resonance imaging (MRI)Chemical Engineering Science, 137
Keyin Liu, Qing Yang, Feng Chen, Yulong Zhao, Xiangwei Meng, Chao Shan, Yanyang Li (2015)
Design and analysis of the cross-linked dual helical micromixer for rapid mixing at low Reynolds numbersMicrofluidics and Nanofluidics, 19
Ying Li, Youzhi Xu, Xiaojun Feng, Bifeng Liu (2012)
A rapid microfluidic mixer for high-viscosity fluids to track ultrafast early folding kinetics of G-quadruplex under molecular crowding conditions.Analytical chemistry, 84 21
N. Ichikawa, K. Hosokawa, R. Maeda (2004)
Interface motion of capillary-driven flow in rectangular microchannel.Journal of colloid and interface science, 280 1
Cha H. (2022)
10.1039/D2LC00197GLab Chip, 22
Aliaa Shallan, P. Smejkal, M. Corban, R. Guijt, M. Breadmore (2014)
Cost-effective three-dimensional printing of visibly transparent microchips within minutes.Analytical chemistry, 86 6
H. Grace (1982)
DISPERSION PHENOMENA IN HIGH VISCOSITY IMMISCIBLE FLUID SYSTEMS AND APPLICATION OF STATIC MIXERS AS DISPERSION DEVICES IN SUCH SYSTEMSChemical Engineering Communications, 14
Hanghang Ding, Xiangtao Zhong, Bo Liu, Liuyong Shi, Teng Zhou, Yonggang Zhu (2021)
Mixing mechanism of a straight channel micromixer based on light-actuated oscillating electroosmosis in low-frequency sinusoidal AC electric fieldMicrofluidics and Nanofluidics, 25
A. Stroock, S. Dertinger, A. Ajdari, I. Mezić, H. Stone, G. Whitesides (2002)
Chaotic Mixer for MicrochannelsScience, 295
C. Jen, Chung-Yi Wu, Yu-Cheng Lin, Ching-Yi Wu (2003)
Design and simulation of the micromixer with chaotic advection in twisted microchannels.Lab on a chip, 3 2
Ying Lin (2015)
Numerical characterization of simple three-dimensional chaotic micromixersChemical Engineering Journal, 277
Chia-Yen Lee, W. Wang, Chan-Chiung Liu, L. Fu (2016)
Passive mixers in microfluidic systems: A reviewChemical Engineering Journal, 288
Micromixers play an important role in the micro total analysis systems (µTAS) that require rapid and effective mixing. However, current micromixers are usually designed to meet the need for mixing at limited Reynolds numbers. Herein, this paper presents a high‐performance 3D micromixer with helical elements over wide Reynolds numbers to achieve efficient mixing and has numerically investigated flow patterns and mixing characteristics accordingly. A coupled numerical model is built to analyze the flow pattern, mixing behavior, residence time distribution (RTD), and mixing performance of the 3D micromixer. Helical elements inside could greatly enhance a secondary flow and induce chaotic advection around. Dean vortices are observed in the micromixer, enormously shortening the RTD and promoting the related mixing effect. Furthermore, the effects of various geometric parameters are systematically investigated to optimize the performance of this 3D micromixer. The optimized micromixer shows excellent mixing ability over wide Reynolds numbers ranging from 0.01 to 2333.3, with an efficiency of over 94%. In addition, the numerical results are proved well consistent with analytical and experimental data correspondingly. Therefore, this work would potentially expand the use scope of 3D micromixers and provide a constructive strategy to develop essential parts involving the mixing or reacting process in µTAS.
Advanced Theory and Simulations – Wiley
Published: May 1, 2023
Keywords: flow pattern; helical element; micromixer; mixing characteristic; secondary flow
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.