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Optic nerve head infiltration in acute leukemia in children: An indication for emergency optic nerve radiation therapy

Optic nerve head infiltration in acute leukemia in children: An indication for emergency optic... Two pediatric patients with acute leukemia who developed optic nerve head leukemic infiltration are presented. In one patient both eyes were involved at diagnosis as well as her central nervous system. Despite systemic and intrathecal chemotherapy she lost her vision within a few weeks. Cranial irradiation at that point could not reverse this outcome. In the second patient optic nerve head infiltration was found a few months after diagnosis, treated promptly with cranial irradiation and her vision was saved. Her central nervous system (CNS) was not involved at any time. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatric Blood & Cancer Wiley

Optic nerve head infiltration in acute leukemia in children: An indication for emergency optic nerve radiation therapy

Pediatric Blood & Cancer , Volume 26 (2) – Feb 1, 1996

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References (17)

Publisher
Wiley
Copyright
Copyright © 1996 Wiley Subscription Services, Inc., A Wiley Company
ISSN
1545-5009
eISSN
1545-5017
DOI
10.1002/(SICI)1096-911X(199602)26:2<101::AID-MPO6>3.0.CO;2-P
Publisher site
See Article on Publisher Site

Abstract

Two pediatric patients with acute leukemia who developed optic nerve head leukemic infiltration are presented. In one patient both eyes were involved at diagnosis as well as her central nervous system. Despite systemic and intrathecal chemotherapy she lost her vision within a few weeks. Cranial irradiation at that point could not reverse this outcome. In the second patient optic nerve head infiltration was found a few months after diagnosis, treated promptly with cranial irradiation and her vision was saved. Her central nervous system (CNS) was not involved at any time.

Journal

Pediatric Blood & CancerWiley

Published: Feb 1, 1996

Keywords: ;

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