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Phylogenetic characteristics of HIV‐1 among travelers entering China from Myanmar: A retrospective study

Phylogenetic characteristics of HIV‐1 among travelers entering China from Myanmar: A... INTRODUCTIONAcquired immunodeficiency syndrome (AIDS) caused by Human immunodeficiency virus (HIV) infection is still a harmful infectious disease worldwide. According to the released data from Joint United Nations Program of HIV/AIDS (UNAIDS) in 2015, approximately 36.7 million people were estimated to be living with HIV and about 2.1 million were newly infected worldwide in that year. The AIDS epidemic has been spread to more than 150 countries across six continents. As one of the most affected areas, there were 3.9 million People living with HIV/AIDS in South and Southeast Asia, although its epidemic was recognized later than South Africa.HIV‐1 was characterized with extensive genetic diversity owing to the high mutation and recombination rates during virus replication. Phylogenetically, HIV‐1 could be divided into three distinct groups: M, O, and N group. As the global pandemic group, M group is further subdivided into various subtypes (A‐D, F‐H, J, and K) and multiple recombinant forms, the latter presented as circulating recombinant forms (CRFs) and unique recombinant forms (URFs). In Southeast Asia and neighboring countries, the most prevalent HIV‐1 genotypes are documented as C, B, and CRF01_AE. However, the genotype distribution is dynamic as the CRF prevalence has been increased, and a high prevalence http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Medical Virology Wiley

Phylogenetic characteristics of HIV‐1 among travelers entering China from Myanmar: A retrospective study

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References (35)

Publisher
Wiley
Copyright
© 2017 Wiley Periodicals, Inc.
ISSN
0146-6615
eISSN
1096-9071
DOI
10.1002/jmv.24786
pmid
28198547
Publisher site
See Article on Publisher Site

Abstract

INTRODUCTIONAcquired immunodeficiency syndrome (AIDS) caused by Human immunodeficiency virus (HIV) infection is still a harmful infectious disease worldwide. According to the released data from Joint United Nations Program of HIV/AIDS (UNAIDS) in 2015, approximately 36.7 million people were estimated to be living with HIV and about 2.1 million were newly infected worldwide in that year. The AIDS epidemic has been spread to more than 150 countries across six continents. As one of the most affected areas, there were 3.9 million People living with HIV/AIDS in South and Southeast Asia, although its epidemic was recognized later than South Africa.HIV‐1 was characterized with extensive genetic diversity owing to the high mutation and recombination rates during virus replication. Phylogenetically, HIV‐1 could be divided into three distinct groups: M, O, and N group. As the global pandemic group, M group is further subdivided into various subtypes (A‐D, F‐H, J, and K) and multiple recombinant forms, the latter presented as circulating recombinant forms (CRFs) and unique recombinant forms (URFs). In Southeast Asia and neighboring countries, the most prevalent HIV‐1 genotypes are documented as C, B, and CRF01_AE. However, the genotype distribution is dynamic as the CRF prevalence has been increased, and a high prevalence

Journal

Journal of Medical VirologyWiley

Published: Aug 1, 2017

Keywords: ; ;

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