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Tailoring Gelation Mechanisms for Advanced Hydrogel Applications

Tailoring Gelation Mechanisms for Advanced Hydrogel Applications Hydrogels are one of the most commonly explored classes of biomaterials. Their chemical and structural versatility has enabled their use across a wide range of applications, including tissue engineering, drug delivery, and cell culture. Hydrogels form upon a sol–gel transition, which can be elicited by different triggers designed to enable precise control over hydrogelation kinetics and hydrogel structure. The chosen hydrogelation trigger and chemistry can have a profound effect on the success of the targeted application. In this Progress Report, a critical overview of recent advances in hydrogel design is presented, with a focus on the available strategies used to trigger the formation of hydrogel networks (e.g., temperature, light, ultrasound). These triggers are presented within a new classification system, and their suitability for six key hydrogel‐based applications is assessed. This Progress Report is intended to guide trigger selection for new hydrogel applications and inspire the rational design of new hydrogelation trigger mechanisms. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Advanced Functional Materials Wiley

Tailoring Gelation Mechanisms for Advanced Hydrogel Applications

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References (295)

Publisher
Wiley
Copyright
© 2020 Wiley‐VCH GmbH
ISSN
1616-301X
eISSN
1616-3028
DOI
10.1002/adfm.202002759
Publisher site
See Article on Publisher Site

Abstract

Hydrogels are one of the most commonly explored classes of biomaterials. Their chemical and structural versatility has enabled their use across a wide range of applications, including tissue engineering, drug delivery, and cell culture. Hydrogels form upon a sol–gel transition, which can be elicited by different triggers designed to enable precise control over hydrogelation kinetics and hydrogel structure. The chosen hydrogelation trigger and chemistry can have a profound effect on the success of the targeted application. In this Progress Report, a critical overview of recent advances in hydrogel design is presented, with a focus on the available strategies used to trigger the formation of hydrogel networks (e.g., temperature, light, ultrasound). These triggers are presented within a new classification system, and their suitability for six key hydrogel‐based applications is assessed. This Progress Report is intended to guide trigger selection for new hydrogel applications and inspire the rational design of new hydrogelation trigger mechanisms.

Journal

Advanced Functional MaterialsWiley

Published: Oct 1, 2020

Keywords: ; ; ; ;

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