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LETTERS TO THE EDITOR Considering the cut-off level as poor clinical and modeling practice. We The Importance of positive or negative could further enhance did not rely on SUV for nodule avidity as Being Solid or Partially the capability to detect malignancies. two-thirds of patients in the development cohort did not report a SUV but rather Solid for a Solitary the reader’s impression of the nodule. Luca Bertolaccini, MD, PhD, FCCP, The institutions used in our study rarely Pulmonary Nodule Alberto Terzi, MD 2–4 report SUV for various reasons. We Thoracic Surgery Unit conducted sensitivity analysis by group- Sacro Cuore Research Hospital To the Editor: ing the four categories of avidity into Negrar Verona, Italy We read with interest the article different combinations, and we reported Matteo Salgarello, MD of Stephen A. Deppen et al. about the best prediction model that cross-val- Nuclear Medicine Unit the development and validation of the idated in our data. These analyses were Sacro Cuore Research Hospital Thoracic Research Evaluation And not included in the original article due to Negrar Verona, Italy Treatment lung cancer prediction space limitations. From a purely statis- model. One of the variables used in the tical stand point, considering SUV as a model was the 18F-fluorodeoxyglucose possibly nonlinear
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Feb 1, 2015
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