Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

A systematic review of perceived risks, psychological and behavioral impacts of genetic testing

A systematic review of perceived risks, psychological and behavioral impacts of genetic testing January 2008  Vol. 10  No. 1 review A systematic review of perceived risks, psychological and behavioral impacts of genetic testing 1 1 1 Jodi T. Heshka, MD, MSc , Crystal Palleschi, MSc , Heather Howley, MSc , 1 1,2 Brenda Wilson, MRCP (UK), MFPHM (UK) , and Philip S. Wells, MD, FRCPC Genetic testing may enable early disease detection, targeted surveillance, and result in effective prevention strategies. Knowledge of genetic risk may also enable behavioral change. However, the impact of carrier status from the psychological, behavior, and perceived risk perspectives is not well understood. We conducted a systematic review to summarize the available literature on these elements. An extensive literature review was performed to identify studies that measured the perceived risk, psychological, and/or behavioral impacts of genetic testing on individuals. The search was not limited to specific diseases but excluded the impacts of testing for single gene disorders. A total of 35 articles and 30 studies were included. The studies evaluated hereditary nonpolyposis colorectal carcinoma, hereditary breast and ovarian cancer, and Alzheimer disease. For affective outcomes, the majority of the studies reported negative effects on carriers but these were short-lived. For behavioral outcomes, an increase in screening http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Genetics in Medicine Wolters Kluwer Health

A systematic review of perceived risks, psychological and behavioral impacts of genetic testing

Genetics in Medicine , Volume 10 (1) – Jan 1, 2008

Loading next page...
 
/lp/wolters-kluwer-health/a-systematic-review-of-perceived-risks-psychological-and-behavioral-FNAa5xxNbB

References (49)

ISSN
1098-3600
DOI
10.1097/GIM.0b013e31815f524f
pmid
18197053
Publisher site
See Article on Publisher Site

Abstract

January 2008  Vol. 10  No. 1 review A systematic review of perceived risks, psychological and behavioral impacts of genetic testing 1 1 1 Jodi T. Heshka, MD, MSc , Crystal Palleschi, MSc , Heather Howley, MSc , 1 1,2 Brenda Wilson, MRCP (UK), MFPHM (UK) , and Philip S. Wells, MD, FRCPC Genetic testing may enable early disease detection, targeted surveillance, and result in effective prevention strategies. Knowledge of genetic risk may also enable behavioral change. However, the impact of carrier status from the psychological, behavior, and perceived risk perspectives is not well understood. We conducted a systematic review to summarize the available literature on these elements. An extensive literature review was performed to identify studies that measured the perceived risk, psychological, and/or behavioral impacts of genetic testing on individuals. The search was not limited to specific diseases but excluded the impacts of testing for single gene disorders. A total of 35 articles and 30 studies were included. The studies evaluated hereditary nonpolyposis colorectal carcinoma, hereditary breast and ovarian cancer, and Alzheimer disease. For affective outcomes, the majority of the studies reported negative effects on carriers but these were short-lived. For behavioral outcomes, an increase in screening

Journal

Genetics in MedicineWolters Kluwer Health

Published: Jan 1, 2008

There are no references for this article.