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Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Alterations in Brain and Immune Function Produced by Mindfulness Meditation Alterations in Brain and Immune Function Produced by Mindfulness Meditation RICHARD J. DAVIDSON,PHD, JON KABAT-ZINN,PHD, JESSICA SCHUMACHER, MS, MELISSA ROSENKRANZ, BA, DANIEL MULLER, MD, PHD, SAKI F. SANTORELLI,EDD, FERRIS URBANOWSKI, MA, ANNE HARRINGTON,PHD, KATHERINE BONUS,MA, AND JOHN F. SHERIDAN,PHD Objective: The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored. We performed a randomized, controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees. Methods: We measured brain electrical activity before and immediately after, and then 4 months after an 8-week training program in mindfulness meditation. Twenty-five subjects were tested in the meditation group. A wait-list control group (N  16) was tested at the same points in time as the meditators. At the end of the 8-week period, subjects in both groups were vaccinated with influenza vaccine. Results: We report for the first time significant increases in left-sided anterior activation, a pattern previously associated with positive affect, in the meditators compared with the nonmedi- tators. We also found significant increases in http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychosomatic Medicine Wolters Kluwer Health

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Psychosomatic Medicine , Volume 65 (4) – Jul 1, 2003

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Copyright
Copyright © 2003 by the American Psychosomatic Society
ISSN
0033-3174
eISSN
1534-7796
DOI
10.1097/01.PSY.0000077505.67574.E3
Publisher site
See Article on Publisher Site

Abstract

Alterations in Brain and Immune Function Produced by Mindfulness Meditation RICHARD J. DAVIDSON,PHD, JON KABAT-ZINN,PHD, JESSICA SCHUMACHER, MS, MELISSA ROSENKRANZ, BA, DANIEL MULLER, MD, PHD, SAKI F. SANTORELLI,EDD, FERRIS URBANOWSKI, MA, ANNE HARRINGTON,PHD, KATHERINE BONUS,MA, AND JOHN F. SHERIDAN,PHD Objective: The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored. We performed a randomized, controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees. Methods: We measured brain electrical activity before and immediately after, and then 4 months after an 8-week training program in mindfulness meditation. Twenty-five subjects were tested in the meditation group. A wait-list control group (N  16) was tested at the same points in time as the meditators. At the end of the 8-week period, subjects in both groups were vaccinated with influenza vaccine. Results: We report for the first time significant increases in left-sided anterior activation, a pattern previously associated with positive affect, in the meditators compared with the nonmedi- tators. We also found significant increases in

Journal

Psychosomatic MedicineWolters Kluwer Health

Published: Jul 1, 2003

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