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Assessing the Validity of a Model to Identify Patients for Lymph Node Biopsy

Assessing the Validity of a Model to Identify Patients for Lymph Node Biopsy Assessing the Validity of a Model to Identify Patients for Lymph Node Biopsy Yasuharu Tokuda, MD, Yuka Kishaba, MD, Jinichi Kato, MD, and Nobuhiko Nakazato, MD Vassilakopoulos and Pangalis developed a multivariate Abstract: A model to identify adult patients with malignant or gran- model to differentiate adult patients with lymphadenopathy ulomatous lymphadenopathy demonstrated a sensitivity/specificity whose biopsy results would lead to treatment (granulomatous or of 0.97/0.91 in the reference sample by Vassilakopoulos and malignant lymph nodes) from those whose biopsy results would Pangalis. The current study tests the performance of the model in a not lead to treatment (normal, hyperplastic, or benign inflam- new sample (n = 151) of patients with peripheral lymphadenopathy. Patient charts were reviewed for the biopsy diagnosis and for the 6 matory lymph nodes). In their original report, 6 variables (age, variables in the model (age, tenderness, size, generalized pruritus, tenderness, size, generalized pruritus, supraclavicular lymph- supraclavicular lymphadenopathy, and texture). The prevalence rate adenopathy, and texture) assigned 92% of the patients to the of malignancy or granuloma in the validation sample was 0.26. When correct histopathologic group. The model thus appeared to be a the cutoff point of 1 was used, as in the original http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Medicine Wolters Kluwer Health

Assessing the Validity of a Model to Identify Patients for Lymph Node Biopsy

Medicine , Volume 82 (6) – Nov 1, 2003

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ISSN
0025-7974
eISSN
1536-5964
DOI
10.1097/01.md.0000100047.15804.b6
pmid
14663291
Publisher site
See Article on Publisher Site

Abstract

Assessing the Validity of a Model to Identify Patients for Lymph Node Biopsy Yasuharu Tokuda, MD, Yuka Kishaba, MD, Jinichi Kato, MD, and Nobuhiko Nakazato, MD Vassilakopoulos and Pangalis developed a multivariate Abstract: A model to identify adult patients with malignant or gran- model to differentiate adult patients with lymphadenopathy ulomatous lymphadenopathy demonstrated a sensitivity/specificity whose biopsy results would lead to treatment (granulomatous or of 0.97/0.91 in the reference sample by Vassilakopoulos and malignant lymph nodes) from those whose biopsy results would Pangalis. The current study tests the performance of the model in a not lead to treatment (normal, hyperplastic, or benign inflam- new sample (n = 151) of patients with peripheral lymphadenopathy. Patient charts were reviewed for the biopsy diagnosis and for the 6 matory lymph nodes). In their original report, 6 variables (age, variables in the model (age, tenderness, size, generalized pruritus, tenderness, size, generalized pruritus, supraclavicular lymph- supraclavicular lymphadenopathy, and texture). The prevalence rate adenopathy, and texture) assigned 92% of the patients to the of malignancy or granuloma in the validation sample was 0.26. When correct histopathologic group. The model thus appeared to be a the cutoff point of 1 was used, as in the original

Journal

MedicineWolters Kluwer Health

Published: Nov 1, 2003

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