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Biology of plasmacytoid dendritic cells and natural killer cells in HIV-1 infection

Biology of plasmacytoid dendritic cells and natural killer cells in HIV-1 infection Biology of plasmacytoid dendritic cells and natural killer cells in HIV-1 infection a b b a Viswanathan Lakshmanan , Galit Alter , Marcus Altfeld and Nina Bhardwaj Abbreviations Purpose This review summarizes recent literature on the biology of APOBEC apolipoprotein B mRNA editing enzyme, catalytic polypeptide BDCA blood dendritic cell antigen dendritic cells and natural killer cells in HIV-1 infection and CCL CC chemokine ligand the importance of crosstalk between them in the CCR CC chemokine receptor cDC conventional/myeloid dendritic cell development of strong antiviral immunity. CXCR CXC chemokine receptor Recent findings DC-SIGN dendritic cell-specific, intercellular adhesion molecule-grabbing non-integrin Type I interferons produced by dendritic cells in response to HMBG high mobility group box group HIV-1 have been suggested to act as a double-edged IDO indoleamine 2,3-dioxygenase IFN interferon sword, stemming HIV-1 replication on the one hand and ILT immunoglobulin-like transcript causing T-cell loss on the other. Recent epidemiologic IRF interferon regulatory factor KIR killer cell immunoglobulin-like receptor evidence demonstrates a strong association between the Mda melanoma differentiation associated gene natural killer cell receptor KIR3DS1 (along with its NK natural killer pDC plasmacytoid dendritic cell presumed ligand HLA-B Bw4-80I) in the control of HIV-1 RIG retinoic acid inducible protein http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in HIV and Aids Wolters Kluwer Health

Biology of plasmacytoid dendritic cells and natural killer cells in HIV-1 infection

Current Opinion in HIV and Aids , Volume 2 (3) – May 1, 2007

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ISSN
1746-630X
eISSN
1746-6318
DOI
10.1097/COH.0b013e32810996db
pmid
19372886
Publisher site
See Article on Publisher Site

Abstract

Biology of plasmacytoid dendritic cells and natural killer cells in HIV-1 infection a b b a Viswanathan Lakshmanan , Galit Alter , Marcus Altfeld and Nina Bhardwaj Abbreviations Purpose This review summarizes recent literature on the biology of APOBEC apolipoprotein B mRNA editing enzyme, catalytic polypeptide BDCA blood dendritic cell antigen dendritic cells and natural killer cells in HIV-1 infection and CCL CC chemokine ligand the importance of crosstalk between them in the CCR CC chemokine receptor cDC conventional/myeloid dendritic cell development of strong antiviral immunity. CXCR CXC chemokine receptor Recent findings DC-SIGN dendritic cell-specific, intercellular adhesion molecule-grabbing non-integrin Type I interferons produced by dendritic cells in response to HMBG high mobility group box group HIV-1 have been suggested to act as a double-edged IDO indoleamine 2,3-dioxygenase IFN interferon sword, stemming HIV-1 replication on the one hand and ILT immunoglobulin-like transcript causing T-cell loss on the other. Recent epidemiologic IRF interferon regulatory factor KIR killer cell immunoglobulin-like receptor evidence demonstrates a strong association between the Mda melanoma differentiation associated gene natural killer cell receptor KIR3DS1 (along with its NK natural killer pDC plasmacytoid dendritic cell presumed ligand HLA-B Bw4-80I) in the control of HIV-1 RIG retinoic acid inducible protein

Journal

Current Opinion in HIV and AidsWolters Kluwer Health

Published: May 1, 2007

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