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Bronchogenic Carcinoma after Lung Transplantation: Characteristics and Outcomes

Bronchogenic Carcinoma after Lung Transplantation: Characteristics and Outcomes ORIGINAL ARTICLE Bronchogenic Carcinoma after Lung Transplantation: Characteristics and Outcomes Omar A. Minai, MD,* Sonia Shah, MD,* Peter Mazzone, MD,* Marie M. Budev, MD,* Debasis Sahoo, MBBS,* Sudish Murthy, MD,† David Mason, MD,† Gosta Pettersson, MD,† and Atul C. Mehta, MBBS* bronchogenic cancer (BCa) in the native lung. Pulmonary Background: Lung cancer may occur in the lung transplant popu- nodules or masses in LTXP recipients may represent a variety lation because many patients are former smokers. Not much is of etiologic possibilities and occur in native or transplanted known about risk factors and outcomes in these patients. lung. Lung transplant recipients are also at an increased risk Methods: We performed a search of the lung transplant database at of malignancy because of prolonged immunosuppression. our institution to identify patients who had been diagnosed with lung Previous reports suggest that BCa are the third most common cancer. Records and reports were reviewed for demographics, risk type of malignancy occurring after solid-organ transplanta- factors for malignancy, lung transplant characteristics, radiographic tion with a frequency similar to that in the general popula- characteristics, treatment, and outcomes. tion. Nevertheless, limited information exists in literature Results: We identified 12 lung transplant patients with broncho- http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Thoracic Oncology Wolters Kluwer Health

Bronchogenic Carcinoma after Lung Transplantation: Characteristics and Outcomes

Mehta, Atul C.
Journal of Thoracic Oncology , Volume 3 (12) – Dec 1, 2008
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ISSN
1556-0864
DOI
10.1097/JTO.0b013e31818e1259
pmid
19057264
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE Bronchogenic Carcinoma after Lung Transplantation: Characteristics and Outcomes Omar A. Minai, MD,* Sonia Shah, MD,* Peter Mazzone, MD,* Marie M. Budev, MD,* Debasis Sahoo, MBBS,* Sudish Murthy, MD,† David Mason, MD,† Gosta Pettersson, MD,† and Atul C. Mehta, MBBS* bronchogenic cancer (BCa) in the native lung. Pulmonary Background: Lung cancer may occur in the lung transplant popu- nodules or masses in LTXP recipients may represent a variety lation because many patients are former smokers. Not much is of etiologic possibilities and occur in native or transplanted known about risk factors and outcomes in these patients. lung. Lung transplant recipients are also at an increased risk Methods: We performed a search of the lung transplant database at of malignancy because of prolonged immunosuppression. our institution to identify patients who had been diagnosed with lung Previous reports suggest that BCa are the third most common cancer. Records and reports were reviewed for demographics, risk type of malignancy occurring after solid-organ transplanta- factors for malignancy, lung transplant characteristics, radiographic tion with a frequency similar to that in the general popula- characteristics, treatment, and outcomes. tion. Nevertheless, limited information exists in literature Results: We identified 12 lung transplant patients with broncho-

Journal

Journal of Thoracic Oncology – Wolters Kluwer Health

Published: Dec 1, 2008

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