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ORIGINAL ARTICLE Combined Evaluation of Postoperative Serum Levels of Carcinoembryonic Antigen Less than or Equal to 2.5 ng/ml and Absence of Vascular Invasion may Predict no Recurrence of Stage I Adenocarcinoma Lung Cancer Kosuke Kashiwabara, MD, Syoh Saeki, MD, Ji-ichiro Sasaki, MD, Masanobu Nomura, MD, and Hirotsugu Kohrogi, MD ccording to the 2007 American College of Chest Physi- Study Objectives: It has been reported that high levels of serum Acians guidelines for diagnosis and management for lung carcinoembryonic antigen (CEA) after surgery, or the presence of cancer, for both stage IA and IB non-small cell lung cancer vascular invasion or both, are strong indicators of postoperative (NSCLC) patients who had the curative resection, adjuvant recurrence in patients with non-small cell lung cancer. The chemotherapy has not been recommended for routine use. In purpose of this study is to evaluate which kind of patients with Japan, oral uracil/tegafur (UFT) therapy is performed as p-stage I adenocarcinoma need adjuvant chemotherapy, using adjuvant chemotherapy in pathologic (p-) stage IB adenocar- those predictors. cinoma patients because it has been reported that a 5-year Patients and Methods: We studied 136 patients with curatively survival rate is 85% in the UFT group compared with 74%
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Dec 1, 2008
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