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ORIGINAL ARTICLE Exercise Capacity, Lung Function, and Quality of Life After Interventional Bronchoscopy P. Leland Oviatt, MD,* David R. Stather, MD,* Gae¨tane Michaud, MD,† Paul MacEachern, MD,* and Alain Tremblay, MDCM* also lead to airway compromise by direct extension or via Introduction: Malignant airway obstruction accounts for significant metastasis to the airway or surrounding lymph nodes. morbidity and mortality in patients with lung and metastatic cancer. Interventional bronchoscopy techniques have emerged We prospectively assessed the effects of bronchoscopic interven- in the recent years as viable palliative options in the treatment tions for the treatment of malignant airway obstruction, with specific of malignant central airway obstruction. Although the tech- attention to exercise capacity and quality of life (QoL). nical success of such procedures has been well documented, Methods: This is a prospective cohort study. Patients with high- as have short-term improvements in performance status, spi- grade, symptomatic central malignant airway obstruction were as- rometry, and dyspnea scores, little is known regarding their sessed at baseline and then at days 30, 90, and 180 after broncho- impact on overall quality of life, objective measurements of scopic intervention with spirometry, 6-minute walk test (6MWT), functional status, and symptoms beyond the immediate post-
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Jan 1, 2011
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