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Impact of Preoperative Versus Postoperative Chemotherapy on the Extent and Number of Surgical Procedures in Patients Treated in Randomized Clinical Trials for Breast Cancer

Impact of Preoperative Versus Postoperative Chemotherapy on the Extent and Number of Surgical... ORIGINAL ARTICLES Impact of Preoperative Versus Postoperative Chemotherapy on the Extent and Number of Surgical Procedures in Patients Treated in Randomized Clinical Trials for Breast Cancer Judy C. Boughey, MD, Florentia Peintinger, MD, Funda Meric-Bernstam, MD, Allison C. Perry, MS, PA-C, Kelly K. Hunt, MD, Gildy V. Babiera, MD, S. E. Singletary, MD, Isabelle Bedrosian, MD, Anthony Lucci, MD, Aman U. Buzdar, MD, Lajos Pusztai, MD, PhD, and Henry M. Kuerer, MD, PhD he use of preoperative chemotherapy for breast cancer is Objective: To determine the effect of preoperative chemotherapy on Tbecoming a widely accepted treatment option. Survival of the volume of tissue excised and the number of breast operations in breast cancer patients treated with preoperative chemotherapy patients undergoing breast-conserving therapy (BCT). has been shown to be equivalent to that of breast cancer Summary Background Data: Preoperative chemotherapy is in- 1,2 patients treated with postoperative chemotherapy. How- creasingly being used for breast cancer and increases rates of BCT. ever, preoperative therapy has advantages: it permits in vivo Its impact on the extent of surgery and the number of surgical assessment of tumor response to chemotherapy and increases procedures in BCT has never been fully defined. The extent of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Surgery Wolters Kluwer Health

Impact of Preoperative Versus Postoperative Chemotherapy on the Extent and Number of Surgical Procedures in Patients Treated in Randomized Clinical Trials for Breast Cancer

Annals of Surgery , Volume 244 (3) – Sep 1, 2006

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References (15)

ISSN
0003-4932
eISSN
1528-1140
DOI
10.1097/01.sla.0000234897.38950.5c
pmid
16926572
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLES Impact of Preoperative Versus Postoperative Chemotherapy on the Extent and Number of Surgical Procedures in Patients Treated in Randomized Clinical Trials for Breast Cancer Judy C. Boughey, MD, Florentia Peintinger, MD, Funda Meric-Bernstam, MD, Allison C. Perry, MS, PA-C, Kelly K. Hunt, MD, Gildy V. Babiera, MD, S. E. Singletary, MD, Isabelle Bedrosian, MD, Anthony Lucci, MD, Aman U. Buzdar, MD, Lajos Pusztai, MD, PhD, and Henry M. Kuerer, MD, PhD he use of preoperative chemotherapy for breast cancer is Objective: To determine the effect of preoperative chemotherapy on Tbecoming a widely accepted treatment option. Survival of the volume of tissue excised and the number of breast operations in breast cancer patients treated with preoperative chemotherapy patients undergoing breast-conserving therapy (BCT). has been shown to be equivalent to that of breast cancer Summary Background Data: Preoperative chemotherapy is in- 1,2 patients treated with postoperative chemotherapy. How- creasingly being used for breast cancer and increases rates of BCT. ever, preoperative therapy has advantages: it permits in vivo Its impact on the extent of surgery and the number of surgical assessment of tumor response to chemotherapy and increases procedures in BCT has never been fully defined. The extent of

Journal

Annals of SurgeryWolters Kluwer Health

Published: Sep 1, 2006

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