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International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics*

International pediatric sepsis consensus conference: Definitions for sepsis and organ... Special Article International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics* Brahm Goldstein, MD; Brett Giroir, MD; Adrienne Randolph, MD; and the Members of the International Consensus Conference on Pediatric Sepsis Objective: Although general definitions of the sepsis contin- ables. All conference participants approved the final draft of uum have been published for adults, no such work has been done the proceedings of the meeting. for the pediatric population. Physiologic and laboratory variables Results: Conference attendees modified the current criteria used to define the systemic inflammatory response syndrome used to define SIRS and sepsis in adults to incorporate pediatric (SIRS) and organ dysfunction require modification for the devel- physiologic variables appropriate for the following subcategories opmental stages of children. An international panel of 20 experts of children: newborn, neonate, infant, child, and adolescent. In in sepsis and clinical research from five countries (Canada, addition, the SIRS definition was modified so that either criteria France, Netherlands, United Kingdom, and United States) was for fever or white blood count had to be met. We also defined convened to modify the published adult consensus definitions of various organ dysfunction categories, severe sepsis, and septic infection, sepsis, severe sepsis, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Pediatric Critical Care Medicine Wolters Kluwer Health

International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics*

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References (62)

ISSN
1529-7535
eISSN
1947-3893
DOI
10.1097/01.PCC.0000149131.72248.E6
pmid
15636651
Publisher site
See Article on Publisher Site

Abstract

Special Article International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics* Brahm Goldstein, MD; Brett Giroir, MD; Adrienne Randolph, MD; and the Members of the International Consensus Conference on Pediatric Sepsis Objective: Although general definitions of the sepsis contin- ables. All conference participants approved the final draft of uum have been published for adults, no such work has been done the proceedings of the meeting. for the pediatric population. Physiologic and laboratory variables Results: Conference attendees modified the current criteria used to define the systemic inflammatory response syndrome used to define SIRS and sepsis in adults to incorporate pediatric (SIRS) and organ dysfunction require modification for the devel- physiologic variables appropriate for the following subcategories opmental stages of children. An international panel of 20 experts of children: newborn, neonate, infant, child, and adolescent. In in sepsis and clinical research from five countries (Canada, addition, the SIRS definition was modified so that either criteria France, Netherlands, United Kingdom, and United States) was for fever or white blood count had to be met. We also defined convened to modify the published adult consensus definitions of various organ dysfunction categories, severe sepsis, and septic infection, sepsis, severe sepsis,

Journal

Pediatric Critical Care MedicineWolters Kluwer Health

Published: Jan 1, 2005

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