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Interobserver Agreement in the Nuclear Grading of Primary Pulmonary Adenocarcinoma

Interobserver Agreement in the Nuclear Grading of Primary Pulmonary Adenocarcinoma ORIGINAL ARTICLE Interobserver Agreement in the Nuclear Grading of Primary  Pulmonary Adenocarcinoma Yoshimasa Nakazato, MD,*† Akiko Miyagi Maeshima, MD, ‡ Yuichi Ishikawa, MD,§ Yasushi Yatabe, MD,║ Junya Fukuoka, MD,¶ Tomoyuki Yokose, MD,# Yasuhiko Tomita, MD,** Yuko Minami, MD,†† Hisao Asamura, MD, ‡‡ Keisei Tachibana, MD, §§ Tomoyuki Goya, MD, §§ and Masayuki Noguchi, MD†† a significantly better prognosis (5-year disease-free survival rate; Introduction: Nuclear grading involves an evaluation of the size 91.8% ± 2.7) than the positive cases did (68.6% ± 3.1). XXX and shape of nuclei and the percentage of tumor cells that are in the Conclusion: Nuclear grading is practical for prognostic evaluation mitotic phase. To estimate the degree of aggressiveness, this approach of pulmonary adenocarcinoma. The interobserver agreement for has been applied to various types of carcinomas, such as breast carci- nuclear grading is significantly higher than for histological classi- noma and pulmonary adenocarcinoma (Nakazato et al.). In the pres- XX fications and the extent of the lepidic pattern. Nuclear grading is a ent study, we estimated and evaluated the interobserver variability of reliable prognostic indicator for small adenocarcinomas. nuclear grading in primary pulmonary adenocarcinomas. Methods: We selected 122 primary pulmonary adenocarcinomas Key Words: Nuclear grading, Pulmonary adenocarcinoma, measuring 2 cm or less in http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Thoracic Oncology Wolters Kluwer Health

Interobserver Agreement in the Nuclear Grading of Primary Pulmonary Adenocarcinoma

Noguchi, Masayuki
Journal of Thoracic Oncology , Volume 8 (6) – Jun 1, 2013
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Copyright
Copyright © 2013 by the International Association for the Study of Lung Cancer
ISSN
1556-0864
DOI
10.1097/JTO.0b013e318288dbd8
pmid
23676557
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE Interobserver Agreement in the Nuclear Grading of Primary  Pulmonary Adenocarcinoma Yoshimasa Nakazato, MD,*† Akiko Miyagi Maeshima, MD, ‡ Yuichi Ishikawa, MD,§ Yasushi Yatabe, MD,║ Junya Fukuoka, MD,¶ Tomoyuki Yokose, MD,# Yasuhiko Tomita, MD,** Yuko Minami, MD,†† Hisao Asamura, MD, ‡‡ Keisei Tachibana, MD, §§ Tomoyuki Goya, MD, §§ and Masayuki Noguchi, MD†† a significantly better prognosis (5-year disease-free survival rate; Introduction: Nuclear grading involves an evaluation of the size 91.8% ± 2.7) than the positive cases did (68.6% ± 3.1). XXX and shape of nuclei and the percentage of tumor cells that are in the Conclusion: Nuclear grading is practical for prognostic evaluation mitotic phase. To estimate the degree of aggressiveness, this approach of pulmonary adenocarcinoma. The interobserver agreement for has been applied to various types of carcinomas, such as breast carci- nuclear grading is significantly higher than for histological classi- noma and pulmonary adenocarcinoma (Nakazato et al.). In the pres- XX fications and the extent of the lepidic pattern. Nuclear grading is a ent study, we estimated and evaluated the interobserver variability of reliable prognostic indicator for small adenocarcinomas. nuclear grading in primary pulmonary adenocarcinomas. Methods: We selected 122 primary pulmonary adenocarcinomas Key Words: Nuclear grading, Pulmonary adenocarcinoma, measuring 2 cm or less in

Journal

Journal of Thoracic Oncology – Wolters Kluwer Health

Published: Jun 1, 2013

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