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ORIGINAL ARTICLE Intraoperative Sentinel Node Mapping with Technitium-99 in Lung Cancer Results of CALGB 140203 Multicenter Phase II Trial Michael J. Liptay, MD, Thomas A. D’amico, MD, Chumy Nwogu, MD, Todd L. Demmy, MD, Xiaofei F. Wang, PhD, Lin Gu, PhD, Virginia R. Litle, MD, Scott J. Swanson, and Leslie J. Kohman, MD; for the Thoracic Surgery Subcommittee of the Cancer and Leukemia Group B n the United States, lung cancer remains the number one Introduction: Sentinel node mapping with radioactive technetium Isource of cancer-related mortality in both men and women. in non-small cell lung cancer has been shown to be feasible in Over 160,000 deaths will be attributed to lung cancer in several single institution reports. The Cancer and Leukemia Group 2008. Complete surgical resection for localized disease is the B designed a phase II trial to test a standardized method of this most viable option for sustained remission or cure. Nonethe- technique in a multi-institutional setting. If validated, the technique less the 5 year survival after complete resection of stage I could provide a more accurate and sensitive way to identify lymph tumors is only 60 to 70%. The patients who relapse after node metastases. complete resection
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Feb 1, 2009
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