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“Salvage” Surgery for Primary Mediastinal Malignancies Is it Worthwhile?

“Salvage” Surgery for Primary Mediastinal Malignancies Is it Worthwhile? ORIGINAL ARTICLE “Salvage” Surgery for Primary Mediastinal Malignancies Is it Worthwhile? Francesco Petrella, MD,* Francesco Leo, MD, PhD,* Giulia Veronesi, MD,* Piergiorgio Solli, MD, PhD,* Alessandro Borri, MD,* Domenico Galetta, MD,* Roberto Gasparri, MD,* Rosalba Lembo, PhD,† Davide Radice, PhD,‡ Paolo Scanagatta, MD,* and Lorenzo Spaggiari, MD, PhD*§ Key Words: Mediastinum, Salvage surgery, Mediastinal neo- Introduction: Indications and results of salvage surgery in medi- plasms. astinal tumors are still unclear. This study analyzes a single- center experience to assess its mortality, morbidity, and long- (J Thorac Oncol. 2008;3: 53–58) term results. Methods: Mediastinal salvage surgery (MSS) was defined as sur- gical resection of persistent or recurrent primary mediastinal tumors ediastinal malignancies are a heterogeneous group of after previous local treatments with curative intent or exclusive Mdiseases most of which are suitable for curative surgical resection, such as thymic tumors, nonseminomatous germ chemotherapy in case of bulky tumors. Clinical data of patients cell tumors (nonresponders after chemotherapy), and mesen- undergoing MSS between 1998 and 2005 were analyzed. Overall chymal malignancies. In the case of extensive disease infil- and disease-specific long-term survival was calculated. trating contiguous vascular, cardiac or pulmonary structures, Results: Twenty-one patients (15 men and 6 women, mean age http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Thoracic Oncology Wolters Kluwer Health

“Salvage” Surgery for Primary Mediastinal Malignancies Is it Worthwhile?

Spaggiari, Lorenzo
Journal of Thoracic Oncology , Volume 3 (1) – Jan 1, 2008
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ISSN
1556-0864
DOI
10.1097/JTO.0b013e31815e6d54
pmid
18166841
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE “Salvage” Surgery for Primary Mediastinal Malignancies Is it Worthwhile? Francesco Petrella, MD,* Francesco Leo, MD, PhD,* Giulia Veronesi, MD,* Piergiorgio Solli, MD, PhD,* Alessandro Borri, MD,* Domenico Galetta, MD,* Roberto Gasparri, MD,* Rosalba Lembo, PhD,† Davide Radice, PhD,‡ Paolo Scanagatta, MD,* and Lorenzo Spaggiari, MD, PhD*§ Key Words: Mediastinum, Salvage surgery, Mediastinal neo- Introduction: Indications and results of salvage surgery in medi- plasms. astinal tumors are still unclear. This study analyzes a single- center experience to assess its mortality, morbidity, and long- (J Thorac Oncol. 2008;3: 53–58) term results. Methods: Mediastinal salvage surgery (MSS) was defined as sur- gical resection of persistent or recurrent primary mediastinal tumors ediastinal malignancies are a heterogeneous group of after previous local treatments with curative intent or exclusive Mdiseases most of which are suitable for curative surgical resection, such as thymic tumors, nonseminomatous germ chemotherapy in case of bulky tumors. Clinical data of patients cell tumors (nonresponders after chemotherapy), and mesen- undergoing MSS between 1998 and 2005 were analyzed. Overall chymal malignancies. In the case of extensive disease infil- and disease-specific long-term survival was calculated. trating contiguous vascular, cardiac or pulmonary structures, Results: Twenty-one patients (15 men and 6 women, mean age

Journal

Journal of Thoracic Oncology – Wolters Kluwer Health

Published: Jan 1, 2008

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