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ORIGINAL ARTICLE Looking Beyond Surveillance, Epidemiology, and End Results Patterns of Chemotherapy Administration for Advanced Non-small Cell Lung Cancer in a Contemporary, Diverse Population Drew W. Rasco, MD,* Jingsheng Yan, PhD,† Yang Xie, PhD,† Jonathan E. Dowell, MD,* and David E. Gerber, MD* Key Words: Non small-cell lung cancer, Chemotherapy, Metastatic, Introduction: Chemotherapy prolongs survival without substan- Practice patterns, Insurance. tially impairing quality of life for medically fit patients with ad- (J Thorac Oncol. 2010;5: 1529–1535) vanced non-small cell lung cancer (NSCLC), but population-based studies have shown that only 20 to 30% of these patients receive chemotherapy. These earlier studies have relied on Medicare-linked hemotherapy has a well-defined role in the treatment of Surveillance, Epidemiology, and End Results (SEER) data, thus ex- Cmedically fit patients with advanced non-small cell lung cluding the 30 to 35% of lung cancer patients younger than 65 years. cancer (NSCLC). Compared with best supportive care, che- Therefore, we determined the use of chemotherapy in a contemporary, motherapy prolongs overall survival without substantially diverse NSCLC population encompassing all patient ages. 1–5 impairing quality of life. Nevertheless, population-based Methods: We performed a retrospective analysis of patients diag- studies from the 1990s have shown that only 22
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Oct 1, 2010
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