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Lung Cancer Detection with Digital Chest Tomosynthesis Baseline Results from the Observational Study SOS

Lung Cancer Detection with Digital Chest Tomosynthesis Baseline Results from the Observational... ORIGINAL ARTICLE Lung Cancer Detection with Digital Chest Tomosynthesis Baseline Results from the Observational Study SOS Alberto Terzi, MD,* Luca Bertolaccini, MD, PhD,* Andrea Viti, MD,* Liliana Comello, MD,† Donatella Ghirardo, MD,† Roberto Priotto, MD,† and Maurizio Grosso, MD,† for the SOS Study Group ung cancer is the leading cause of cancer-related deaths Introduction: Observational studies consistently support strate- Lin the United States and most of the western and devel- gies for early cancer diagnosis and treatment. Owing to its high oping countries. Most lung cancers are detected when prevalence, mortality rate, and easily identifiable at-risk population patients become symptomatic and have late-stage disease. groups, lung cancer seems ideal for early detection programs. We However, recently, computed tomography (CT) screening present the baseline results of the SOS study, a single-arm observa- for lung cancer has been reported to reduce lung cancer tional study of digital chest tomosynthesis for lung cancer detection mortality. In this regard, the National Lung Screening Trial in an at-risk population. (NLST) showed a 20% reduction in lung cancer-specific Methods: Accrual of study participants started in December 2010 deaths in those patients who had screening performed with and ended in December 2011. Participants considered eligible were chest CT. However, CT is associated http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Thoracic Oncology Wolters Kluwer Health

Lung Cancer Detection with Digital Chest Tomosynthesis Baseline Results from the Observational Study SOS

Grosso, Maurizio
Journal of Thoracic Oncology , Volume 8 (6) – Jun 1, 2013
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Copyright
Copyright © 2013 by the International Association for the Study of Lung Cancer
ISSN
1556-0864
eISSN
1556-1380
DOI
10.1097/JTO.0b013e318292bdef
pmid
23612466
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE Lung Cancer Detection with Digital Chest Tomosynthesis Baseline Results from the Observational Study SOS Alberto Terzi, MD,* Luca Bertolaccini, MD, PhD,* Andrea Viti, MD,* Liliana Comello, MD,† Donatella Ghirardo, MD,† Roberto Priotto, MD,† and Maurizio Grosso, MD,† for the SOS Study Group ung cancer is the leading cause of cancer-related deaths Introduction: Observational studies consistently support strate- Lin the United States and most of the western and devel- gies for early cancer diagnosis and treatment. Owing to its high oping countries. Most lung cancers are detected when prevalence, mortality rate, and easily identifiable at-risk population patients become symptomatic and have late-stage disease. groups, lung cancer seems ideal for early detection programs. We However, recently, computed tomography (CT) screening present the baseline results of the SOS study, a single-arm observa- for lung cancer has been reported to reduce lung cancer tional study of digital chest tomosynthesis for lung cancer detection mortality. In this regard, the National Lung Screening Trial in an at-risk population. (NLST) showed a 20% reduction in lung cancer-specific Methods: Accrual of study participants started in December 2010 deaths in those patients who had screening performed with and ended in December 2011. Participants considered eligible were chest CT. However, CT is associated

Journal

Journal of Thoracic Oncology – Wolters Kluwer Health

Published: Jun 1, 2013

References

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