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Mental and Physical Activities Delay Cognitive Decline in Older Persons With Dementia

Mental and Physical Activities Delay Cognitive Decline in Older Persons With Dementia Mental and Physical Activities Delay Cognitive Decline in Older Persons With Dementia Sheung-Tak Cheng, Ph.D., Pizza K. Chow, M.Sc., You-Qiang Song, Ph.D., Edwin C. S. Yu, M.H., F.H.K.A.M. (Psych.), Alfred C. M. Chan, Ph.D., Tatia M.C. Lee, Ph.D., John H. M. Lam, M.Sc. Objectives: To examine the effects of cognitive stimulation (mahjong) and phys- ical exercise (tai chi [TC]) on cognitive performance in persons with dementia. Design: Cluster-randomized open-label controlled design. Setting: Nursing homes. Participants: One hundred ten residents, most of whom were cholinesterase-inhibitor naive. Inclusion criteria were Mini-Mental State Examination (MMSE) = 10–24 and suffering from at least very mild dementia (Clinical Dementia Rating ≥ 0.5). Exclusion criteria were being bedbound, audio/visual impairment, regular activ- ity participation before study, or contraindications for physical or group activities. Interventions: Homes were randomized into three conditions (mahjong, TC, and simple handicrafts [control]). Activities were conducted three times weekly for 12 weeks. Measurements: Primary outcome was MMSE. Secondary outcomes were immediate/delayed recall, categorical fluency, and digit span. Various biological risk factors, including apolipoprotein E ε4 allele, were included as covariates. Measures were collected at 0 (baseline), 3 (posttreatment), 6, and 9 months. Results: Intent-to- treat analyses were performed using mixed-effects regression. Mahjong’s http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Geriatric Psychiatry Wolters Kluwer Health

Mental and Physical Activities Delay Cognitive Decline in Older Persons With Dementia

American Journal of Geriatric Psychiatry , Volume Publish Ahead of Print – Nov 1, 2012

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Copyright
© 2012 American Association for Geriatric Psychiatry
ISSN
1064-7481
DOI
10.1097/JGP.0b013e31826d6af1
Publisher site
See Article on Publisher Site

Abstract

Mental and Physical Activities Delay Cognitive Decline in Older Persons With Dementia Sheung-Tak Cheng, Ph.D., Pizza K. Chow, M.Sc., You-Qiang Song, Ph.D., Edwin C. S. Yu, M.H., F.H.K.A.M. (Psych.), Alfred C. M. Chan, Ph.D., Tatia M.C. Lee, Ph.D., John H. M. Lam, M.Sc. Objectives: To examine the effects of cognitive stimulation (mahjong) and phys- ical exercise (tai chi [TC]) on cognitive performance in persons with dementia. Design: Cluster-randomized open-label controlled design. Setting: Nursing homes. Participants: One hundred ten residents, most of whom were cholinesterase-inhibitor naive. Inclusion criteria were Mini-Mental State Examination (MMSE) = 10–24 and suffering from at least very mild dementia (Clinical Dementia Rating ≥ 0.5). Exclusion criteria were being bedbound, audio/visual impairment, regular activ- ity participation before study, or contraindications for physical or group activities. Interventions: Homes were randomized into three conditions (mahjong, TC, and simple handicrafts [control]). Activities were conducted three times weekly for 12 weeks. Measurements: Primary outcome was MMSE. Secondary outcomes were immediate/delayed recall, categorical fluency, and digit span. Various biological risk factors, including apolipoprotein E ε4 allele, were included as covariates. Measures were collected at 0 (baseline), 3 (posttreatment), 6, and 9 months. Results: Intent-to- treat analyses were performed using mixed-effects regression. Mahjong’s

Journal

American Journal of Geriatric PsychiatryWolters Kluwer Health

Published: Nov 1, 2012

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