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Non-MALT marginal zone lymphoma

Non-MALT marginal zone lymphoma a,b,c d b,c,e Catherine Thieblemont , Frederic Davi , Maria-Elena Noguera and Josette Brie`re Department of Hemato-Oncology, AP-HP Hoˆpital Purpose of review Saint-Louis, Laboratoire de Pathologie, Universite´ Non-MALT marginal zone lymphoma regroups two subtypes of lymphoma, the splenic Paris Diderot, Sorbonne Paris Cite´ , UMR-S 728, c d Inserm U728, Laboratory of Hematology, AP-HP marginal zone lymphoma (SMZL) and the nodal marginal zone lymphoma (NMZL). Hoˆ pital Pitie´ -Salpe´ trie` re, Laboratory of Hematology Although they share a common cell of origin from the ‘marginal zone’, they display and Department of Pathology, AP-HP Hoˆpital Saint- Louis, Paris, France different clinical characteristics, reflecting probable biological variations according to the organ. Correspondence to Catherine Thieblemont, Department of Hemato-Oncology, Hoˆ pital Saint-Louis, Recent findings 1 Avenue Claude Vellefaux, 75010 Paris, France Within the past decade, new data regarding pathogenic mechanisms as well as Tel: +33 142499236; fax: +33 142499641; e-mail: catherine.thieblemont@sls.aphp.fr therapeutic advances have been reported. Summary Current Opinion in Hematology 2011, 18:273–279 SMZL and NMZL often present with disseminated disease at diagnosis, with specific clinical presentation, SMZL with predominant enlarged splenomegaly and NMZL with disseminated nodal involvement. Diagnosis may be difficult among the small B-cell lymphomas and criteria for diagnosis have http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in Hematology Wolters Kluwer Health

Non-MALT marginal zone lymphoma

Current Opinion in Hematology , Volume 18 (4) – Jul 1, 2011

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References (55)

ISSN
1065-6251
eISSN
1531-7048
DOI
10.1097/MOH.0b013e3283477815
pmid
21577105
Publisher site
See Article on Publisher Site

Abstract

a,b,c d b,c,e Catherine Thieblemont , Frederic Davi , Maria-Elena Noguera and Josette Brie`re Department of Hemato-Oncology, AP-HP Hoˆpital Purpose of review Saint-Louis, Laboratoire de Pathologie, Universite´ Non-MALT marginal zone lymphoma regroups two subtypes of lymphoma, the splenic Paris Diderot, Sorbonne Paris Cite´ , UMR-S 728, c d Inserm U728, Laboratory of Hematology, AP-HP marginal zone lymphoma (SMZL) and the nodal marginal zone lymphoma (NMZL). Hoˆ pital Pitie´ -Salpe´ trie` re, Laboratory of Hematology Although they share a common cell of origin from the ‘marginal zone’, they display and Department of Pathology, AP-HP Hoˆpital Saint- Louis, Paris, France different clinical characteristics, reflecting probable biological variations according to the organ. Correspondence to Catherine Thieblemont, Department of Hemato-Oncology, Hoˆ pital Saint-Louis, Recent findings 1 Avenue Claude Vellefaux, 75010 Paris, France Within the past decade, new data regarding pathogenic mechanisms as well as Tel: +33 142499236; fax: +33 142499641; e-mail: catherine.thieblemont@sls.aphp.fr therapeutic advances have been reported. Summary Current Opinion in Hematology 2011, 18:273–279 SMZL and NMZL often present with disseminated disease at diagnosis, with specific clinical presentation, SMZL with predominant enlarged splenomegaly and NMZL with disseminated nodal involvement. Diagnosis may be difficult among the small B-cell lymphomas and criteria for diagnosis have

Journal

Current Opinion in HematologyWolters Kluwer Health

Published: Jul 1, 2011

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