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EDITORIAL Jean-Louis Pujol, MD,*† Mohammad Chakra, MD,† and Bernard Milleron, MD*‡ 1,2 wo recent articles published in the Journal of Thoracic Oncology are of particular Timportance. It is noteworthy that clinical research is urgently needed in almost all clinical settings of lung cancer from the early stage to metastatic disease. There is a paradox that lung cancer, the leading cause of cancer mortality in both men and women in the developed countries remains the “poor relative” of the clinical cancer research programs with less than 5% of patients enrolling in trials. With a worldwide prognosis remaining almost unchanged during the last decade, it is glaringly obvious that the low participation of patients with thoracic cancer in clinical trials is a major challenge for advancing the field. At the same time, we are facing a dramatic increase in the lung cancer epidemic in many developed countries, particularly in European women, and the situation is worse in many Asian and African countries inasmuch as lung cancer incidence greatly reflects smoking behaviors. Increasing patient participation in thoracic cancer clinical trials is therefore mandatory and the two aforementioned articles help our discussion of this topic: There are four different questions about patients’ participation
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Jan 1, 2008
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