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Patterns of Cardiac Perfusion Abnormalities After Chemoradiotherapy in Patients with Lung Cancer

Patterns of Cardiac Perfusion Abnormalities After Chemoradiotherapy in Patients with Lung Cancer ORIGINAL ARTICLE Patterns of Cardiac Perfusion Abnormalities After Chemoradiotherapy in Patients with Lung Cancer Isis W. Gayed, MD,* H. Helen Liu, PhD,† Xiong Wei, MD,† Zhongxing Liao, MD,‡ Syed Wamique Yusuf, MD,§ Joe Y. Chang, MD,‡ Roland Bassett, PhD, and Ritsuko Komaki, MD‡ ultiple studies in patients with lymphoma or left breast Objective: We evaluated the prevalence of myocardial perfusion Mcancer have demonstrated detrimental effects of radio- defects using myocardial perfusion imaging (MPI) after chemora- 1–6 therapy (RT) on the heart. Researchers have studied the diation or radiation therapy (CRT/RT) in lung cancer patients and effects of RT patients with these two particular types of described their patterns in relation to tumor location. cancer to evaluate the effects of RT because of the longer Methods: MPI in 44 patients who received RT for lung cancer and survival intervals after treatment which allowed for the long- 44 control patients were compared. The two groups were compara- term side effects of RT to manifest. However, investigators ble in risk factors for coronary artery disease. Data regarding tumor have demonstrated the early effects of RT using multiple stage and location, interval between CRT/RT and MPI, and mean 7–9 imaging modalities. For example, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Thoracic Oncology Wolters Kluwer Health

Patterns of Cardiac Perfusion Abnormalities After Chemoradiotherapy in Patients with Lung Cancer

Komaki, Ritsuko
Journal of Thoracic Oncology , Volume 4 (2) – Feb 1, 2009
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ISSN
1556-0864
DOI
10.1097/JTO.0b013e3181990c46
pmid
19179893
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE Patterns of Cardiac Perfusion Abnormalities After Chemoradiotherapy in Patients with Lung Cancer Isis W. Gayed, MD,* H. Helen Liu, PhD,† Xiong Wei, MD,† Zhongxing Liao, MD,‡ Syed Wamique Yusuf, MD,§ Joe Y. Chang, MD,‡ Roland Bassett, PhD, and Ritsuko Komaki, MD‡ ultiple studies in patients with lymphoma or left breast Objective: We evaluated the prevalence of myocardial perfusion Mcancer have demonstrated detrimental effects of radio- defects using myocardial perfusion imaging (MPI) after chemora- 1–6 therapy (RT) on the heart. Researchers have studied the diation or radiation therapy (CRT/RT) in lung cancer patients and effects of RT patients with these two particular types of described their patterns in relation to tumor location. cancer to evaluate the effects of RT because of the longer Methods: MPI in 44 patients who received RT for lung cancer and survival intervals after treatment which allowed for the long- 44 control patients were compared. The two groups were compara- term side effects of RT to manifest. However, investigators ble in risk factors for coronary artery disease. Data regarding tumor have demonstrated the early effects of RT using multiple stage and location, interval between CRT/RT and MPI, and mean 7–9 imaging modalities. For example,

Journal

Journal of Thoracic Oncology – Wolters Kluwer Health

Published: Feb 1, 2009

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