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Persistent hyperinsulinemic hypoglycemia of infancy long-term follow-up after surgical treatment

Persistent hyperinsulinemic hypoglycemia of infancy long-term follow-up after surgical treatment Original article 123 Persistent hyperinsulinemic hypoglycemia of infancy: long-term follow-up after surgical treatment F.N. Wahid, M. Al Onazi, A. Al Rawaf, M. Al Muhaidly, A. Al Otaibi and J. Al Hudhaif Aim The aim of this study was to investigate the medical therapy. Three patients developed diabetes. long-term outcome of six children with persistent None of them had malabsorption, and two patients hyperinsulinemic hypoglycemia of infancy (PHHI) after later developed epilepsy. pancreatectomy who have been followed since 1990 at the Conclusion The earlier the age at diagnosis, the better Riyadh Military Hospital, Riyadh, Kingdom of Saudi Arabia. the neurological outcome. Delayed surgery might be Patients and methods Data from six patients were associated with higher risk of development of diabetes. retrospectively analyzed from chart review. PHHI was Near-total (90–95%) pancreatectomy is the treatment diagnosed on the basis of having high-insulin levels and of choice for PHHI not responsive to medical low-glucose levels and a high insulin-to-glucose ratio. treatment. Ann Pediatr Surg 7:123–125  c 2011 Annals of Lactate, pyruvate, ammonia, and urinary organic acid levels Pediatric Surgery. were recorded and tandem mass spectrometry screening Annals of Pediatric Surgery 2011, 7:123–125 was performed. The patients were assessed radiologically Keywords: Near-total http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Pediatric Surgery Wolters Kluwer Health

Persistent hyperinsulinemic hypoglycemia of infancy long-term follow-up after surgical treatment

Al Hudhaif, J.
Annals of Pediatric Surgery , Volume 7 (4) – Oct 1, 2011
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© 2011 Annals of Pediatric Surgery
eISSN
2090-5394
DOI
10.1097/01.XPS.0000405090.49368.85
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Abstract

Original article 123 Persistent hyperinsulinemic hypoglycemia of infancy: long-term follow-up after surgical treatment F.N. Wahid, M. Al Onazi, A. Al Rawaf, M. Al Muhaidly, A. Al Otaibi and J. Al Hudhaif Aim The aim of this study was to investigate the medical therapy. Three patients developed diabetes. long-term outcome of six children with persistent None of them had malabsorption, and two patients hyperinsulinemic hypoglycemia of infancy (PHHI) after later developed epilepsy. pancreatectomy who have been followed since 1990 at the Conclusion The earlier the age at diagnosis, the better Riyadh Military Hospital, Riyadh, Kingdom of Saudi Arabia. the neurological outcome. Delayed surgery might be Patients and methods Data from six patients were associated with higher risk of development of diabetes. retrospectively analyzed from chart review. PHHI was Near-total (90–95%) pancreatectomy is the treatment diagnosed on the basis of having high-insulin levels and of choice for PHHI not responsive to medical low-glucose levels and a high insulin-to-glucose ratio. treatment. Ann Pediatr Surg 7:123–125  c 2011 Annals of Lactate, pyruvate, ammonia, and urinary organic acid levels Pediatric Surgery. were recorded and tandem mass spectrometry screening Annals of Pediatric Surgery 2011, 7:123–125 was performed. The patients were assessed radiologically Keywords: Near-total

Journal

Annals of Pediatric Surgery – Wolters Kluwer Health

Published: Oct 1, 2011

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