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Predictors of occult neoplasia in women undergoing risk-reducing salpingo-oophorectomy

Predictors of occult neoplasia in women undergoing risk-reducing salpingo-oophorectomy Objective The purpose of this study was to define the rate of neoplasia in prophylactic surgical specimens with the use of a careful surgical and pathologic protocol in a prospective study of high-risk women who were undergoing risk-reducing salpingo-oophorectomy. Outcomes of interest were neoplasia that was identified in surgical specimens and clinical outcomes of women who were undergoing risk-reducing salpingo-oophorectomy. We hypothesized that older age and having a BRCA1 mutation would be predictors for tubal or ovarian neoplasia and that a careful surgical and pathologic protocol would lead to a low rate of subsequent primary peritoneal cancer. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Obstetrics and Gynecology Wolters Kluwer Health

Predictors of occult neoplasia in women undergoing risk-reducing salpingo-oophorectomy

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Publisher
Wolters Kluwer Health
Copyright
Copyright © 2006 Mosby, Inc.
ISSN
0002-9378
DOI
10.1016/j.ajog.2006.03.006
pmid
16731090
Publisher site
See Article on Publisher Site

Abstract

Objective The purpose of this study was to define the rate of neoplasia in prophylactic surgical specimens with the use of a careful surgical and pathologic protocol in a prospective study of high-risk women who were undergoing risk-reducing salpingo-oophorectomy. Outcomes of interest were neoplasia that was identified in surgical specimens and clinical outcomes of women who were undergoing risk-reducing salpingo-oophorectomy. We hypothesized that older age and having a BRCA1 mutation would be predictors for tubal or ovarian neoplasia and that a careful surgical and pathologic protocol would lead to a low rate of subsequent primary peritoneal cancer.

Journal

American Journal of Obstetrics and GynecologyWolters Kluwer Health

Published: Jun 1, 2006

References