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Original a tricle Prognostic Factors Based on Clinicopathological Data Among the Patients with Resected Peripheral Squamous Cell Carcinomas of the Lung Tomonari Kinoshita, MD,* Takashi Ohtsuka, MD, PhD,* Tai Hato, MD, PhD,* Taichiro Goto, MD, PhD,* Ikuo Kamiyama, MD,* Atsushi Tajima, MD, PhD,† Katsura Emoto, MD,‡ Yuichiro Hayashi, MD,‡ and Mitsutomo Kohno, MD, PhD* ung cancer is the most common cause of cancer-related Introduction: Although the incidence of peripheral squamous Ldeath worldwide and squamous cell carcinomas (SqCCs) cell carcinomas (p-SqCCs) of the lung has increased over recent of the lung account for 20–30% of non–small-cell lung can- years, clinicopathological factors influencing prognosis of resected 1,2 cers (NSCLC). SqCCs can be classified into the central p-SqCCs remain unclear. type (c-SqCCs) and the peripheral type (p-SqCCs) accord- Methods: We examined 280 patients who underwent complete ing to the primary location. Although the majority of SqCCs resection of SqCCs and analyzed the clinicopathological features in of the lung have histologically been reported to be c-SqCCs, relation to their overall survival (OS) and recurrence-free survival 3,4 the incidence of p-SqCCs has increased over recent years. (RFS) according to the primary location. Several reports have revealed a low prevalence of lymph node Results: Multivariate analysis of all stages of p-SqCCs patients metastasis in p-SqCCs, especially in tumors 2 cm
Journal of Thoracic Oncology – Wolters Kluwer Health
Published: Dec 1, 2014
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