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Prognostic Factors for Survival after Surgical Palliation of Malignant Pleural Effusion

Prognostic Factors for Survival after Surgical Palliation of Malignant Pleural Effusion ORIGINAL ARTICLE Prognostic Factors for Survival after Surgical Palliation of Malignant Pleural Effusion John E. Pilling, FRCS (CTh), Michael E. Dusmet, MD, George Ladas, FRCS, and Peter Goldstraw, FRCS ecurrent pleural effusions are common in patients with Introduction: To investigate prognostic factors for patient survival Radvanced malignant disease. A wide range of interven- after surgical palliation of malignant pleural effusion (MPE). tions are available to diagnose, control, and palliate the Method: We reviewed 278 consecutive nonoverseas patients (108 symptoms, palliative measures which have been shown to be men, median age: 60 years [range 26 – 89]) undergoing 310 surgical 3–5 effective. There are few identified prognostic factors avail- procedures for palliation of MPE over a 72-month period. There able, especially before surgery, to help the surgeon to select were 195 thoracoscopic talc pleurodesis, 39 pleuroperitoneal shunts, the appropriate modality for palliation. This study seeks to 38 pleurodesis by an intercostal drain, 29 pleural biopsies alone, and analyze factors associated with long-term survival after pal- nine long-term drains. Referring physicians provided survival data. liation of malignant pleural effusion (MPE). The significance of prognostic factors was examined with the log-rank test (Kaplan-Meier), those significant entered a Cox logistic METHODS multivariate regression http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Thoracic Oncology Wolters Kluwer Health

Prognostic Factors for Survival after Surgical Palliation of Malignant Pleural Effusion

Goldstraw, Peter
Journal of Thoracic Oncology , Volume 5 (10) – Oct 1, 2010
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ISSN
1556-0864
DOI
10.1097/JTO.0b013e3181e95cb8
pmid
20802350
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE Prognostic Factors for Survival after Surgical Palliation of Malignant Pleural Effusion John E. Pilling, FRCS (CTh), Michael E. Dusmet, MD, George Ladas, FRCS, and Peter Goldstraw, FRCS ecurrent pleural effusions are common in patients with Introduction: To investigate prognostic factors for patient survival Radvanced malignant disease. A wide range of interven- after surgical palliation of malignant pleural effusion (MPE). tions are available to diagnose, control, and palliate the Method: We reviewed 278 consecutive nonoverseas patients (108 symptoms, palliative measures which have been shown to be men, median age: 60 years [range 26 – 89]) undergoing 310 surgical 3–5 effective. There are few identified prognostic factors avail- procedures for palliation of MPE over a 72-month period. There able, especially before surgery, to help the surgeon to select were 195 thoracoscopic talc pleurodesis, 39 pleuroperitoneal shunts, the appropriate modality for palliation. This study seeks to 38 pleurodesis by an intercostal drain, 29 pleural biopsies alone, and analyze factors associated with long-term survival after pal- nine long-term drains. Referring physicians provided survival data. liation of malignant pleural effusion (MPE). The significance of prognostic factors was examined with the log-rank test (Kaplan-Meier), those significant entered a Cox logistic METHODS multivariate regression

Journal

Journal of Thoracic Oncology – Wolters Kluwer Health

Published: Oct 1, 2010

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