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The current state of cancer family history collection tools in primary care: a systematic review

The current state of cancer family history collection tools in primary care: a systematic... STRUCTURED REVIEW The current state of cancer family history collection tools in primary care: a systematic review 1 2 3 Nadeem Qureshi, MBBS, DM , June C. Carroll, MD , Brenda Wilson, FFPH , 4,5 6 4,7 Pasqualina Santaguida, PhD , Judith Allanson, FRCP , Melissa Brouwers, PhD , 4,5 and Parminder Raina, PhD family history information alone can form the basis for offering Abstract: Systematic collection of family history is a prerequisite for 1,3 patients appropriately tailored preventive interventions. In identifying genetic risk. This study reviewed tools applicable to the addition, the clinical predictive value of even the most accurate primary care assessment of family history of breast, colorectal, ovarian, DNA test depends on penetrance of the gene mutation and and prostate cancer. MEDLINE, EMBASE, CINAHL, and Cochrane requires family history information for test interpretation. Central were searched for publications. All primary study designs were Thus, family history information is potentially useful both as a included. Characteristics of the studies, the family history collection clinical tool in its own right and also as an important adjunct to tools, and the setting were evaluated. Of 40 eligible studies, 18 relevant DNA-based testing. family history tools were identified, with 11 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Genetics in Medicine Wolters Kluwer Health

The current state of cancer family history collection tools in primary care: a systematic review

Genetics in Medicine , Volume 11 (7) – Jul 1, 2009

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References (74)

ISSN
1098-3600
DOI
10.1097/GIM.0b013e3181a7e8e0
pmid
19521245
Publisher site
See Article on Publisher Site

Abstract

STRUCTURED REVIEW The current state of cancer family history collection tools in primary care: a systematic review 1 2 3 Nadeem Qureshi, MBBS, DM , June C. Carroll, MD , Brenda Wilson, FFPH , 4,5 6 4,7 Pasqualina Santaguida, PhD , Judith Allanson, FRCP , Melissa Brouwers, PhD , 4,5 and Parminder Raina, PhD family history information alone can form the basis for offering Abstract: Systematic collection of family history is a prerequisite for 1,3 patients appropriately tailored preventive interventions. In identifying genetic risk. This study reviewed tools applicable to the addition, the clinical predictive value of even the most accurate primary care assessment of family history of breast, colorectal, ovarian, DNA test depends on penetrance of the gene mutation and and prostate cancer. MEDLINE, EMBASE, CINAHL, and Cochrane requires family history information for test interpretation. Central were searched for publications. All primary study designs were Thus, family history information is potentially useful both as a included. Characteristics of the studies, the family history collection clinical tool in its own right and also as an important adjunct to tools, and the setting were evaluated. Of 40 eligible studies, 18 relevant DNA-based testing. family history tools were identified, with 11

Journal

Genetics in MedicineWolters Kluwer Health

Published: Jul 1, 2009

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