Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

The effects of HIV and aging on brain functions proposing a research framework and update on last 3 years’ findings

The effects of HIV and aging on brain functions proposing a research framework and update on... REVIEW URRENT The effects of HIV and aging on brain functions: PINION proposing a research framework and update on last 3 years’ findings a,b,c a,c Lucette A. Cysique and Bruce J. Brew Purpose of review The effect of HIV and aging on brain functions is an increasingly important topic of research: HIV-infected (HIVþ) persons aged 50 represent a growing part of the HIV epidemic. Research is embracing this new axis, but there has been a lack of conceptualization of the factors that are at stake in both aging and HIV. To start to remedy this theoretical limitation, we are proposing a research framework in the hope that it will optimize how research questions and findings are formulated. Moreover, in the light of this proposed research framework, we review the last 3 years’ research findings. Recent findings Our review highlights that as HIVþ persons are aging, there is some signal for acceleration of normal aging processes and facilitated expression of age-associated diseases. Evidence for dramatic neurodegeneration in aging HIVþ persons remains limited and may be different in nature to typical neurodegenerative processes. Also, it should be kept in mind that most HIVþ persons are still below age 60. The vast http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Opinion in HIV and Aids Wolters Kluwer Health

The effects of HIV and aging on brain functions proposing a research framework and update on last 3 years’ findings

Brew, Bruce J.
Current Opinion in HIV and Aids , Volume 9 (4) – Jul 1, 2014
Download PDF
10 pages

Loading next page...
 
/lp/wolters-kluwer-health/the-effects-of-hiv-and-aging-on-brain-functions-proposing-a-research-SstNSI2qO5

References

References for this paper are not available at this time. We will be adding them shortly, thank you for your patience.

Copyright
© 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins
ISSN
1746-630X
eISSN
1746-6318

Abstract

REVIEW URRENT The effects of HIV and aging on brain functions: PINION proposing a research framework and update on last 3 years’ findings a,b,c a,c Lucette A. Cysique and Bruce J. Brew Purpose of review The effect of HIV and aging on brain functions is an increasingly important topic of research: HIV-infected (HIVþ) persons aged 50 represent a growing part of the HIV epidemic. Research is embracing this new axis, but there has been a lack of conceptualization of the factors that are at stake in both aging and HIV. To start to remedy this theoretical limitation, we are proposing a research framework in the hope that it will optimize how research questions and findings are formulated. Moreover, in the light of this proposed research framework, we review the last 3 years’ research findings. Recent findings Our review highlights that as HIVþ persons are aging, there is some signal for acceleration of normal aging processes and facilitated expression of age-associated diseases. Evidence for dramatic neurodegeneration in aging HIVþ persons remains limited and may be different in nature to typical neurodegenerative processes. Also, it should be kept in mind that most HIVþ persons are still below age 60. The vast

Journal

Current Opinion in HIV and Aids – Wolters Kluwer Health

Published: Jul 1, 2014

There are no references for this article.